Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Kaufmann Medical Building, Pittsburgh, PA 15213, USA.
Injury. 2009 Sep;40(9):907-11. doi: 10.1016/j.injury.2009.05.006. Epub 2009 Jun 21.
Numerous articles have examined the pattern of traumatic deaths. Most of these studies have aimed to improve trauma care and raise awareness of avoidable complications. The aim of the present review is to evaluate whether the distribution of complications and mortality has changed.
A review of the published literature to identify studies examining patterns and causes of death following trauma treated in level 1 hospitals published between 1980 and 2008. PubMed was searched using the following terms: Trauma Epidemiology, Injury Pattern, Trauma Deaths, and Causes of Death. Three time periods were differentiated: (n=6, 1980-1989), (n=6, 1990-1999), and (n=10, 2000-2008). The results were limited to the English and/or German language. Manuscripts were analysed to identify the age, injury severity score (ISS), patterns and causes of death mentioned in studies.
Twenty-two publications fulfilled the inclusion criteria for the review. A decrease of haemorrhage-induced deaths (25-15%) has occurred within the last decade. No considerable changes in the incidence and pattern of death were found. The predominant cause of death after trauma continues to be central nervous system (CNS) injury (21.6-71.5%), followed by exsanguination (12.5-26.6%), while sepsis (3.1-17%) and multi-organ failure (MOF) (1.6-9%) continue to be predominant causes of late death.
Comparing manuscripts from the last three decades revealed a reduction in the mortality rate from exsanguination. Rates of the other causes of death appear to be unchanged. These improvements might be explained by developments in the availability of multislice CT, implementation of ATLS concepts and logistics of emergency rescue.
许多文章研究了创伤性死亡的模式。这些研究大多旨在改善创伤治疗并提高对可避免并发症的认识。本综述的目的是评估并发症和死亡率的分布是否发生了变化。
通过检索 1980 年至 2008 年间发表的在一级医院治疗的创伤患者的模式和死亡原因的研究,对已发表的文献进行了回顾。使用以下术语在 PubMed 上搜索:创伤流行病学、损伤模式、创伤死亡和死亡原因。区分了三个时间段:(n=6,1980-1989 年)、(n=6,1990-1999 年)和(n=10,2000-2008 年)。结果仅限于英语和/或德语文献。分析了手稿以确定研究中提到的年龄、损伤严重程度评分(ISS)、死亡模式和原因。
有 22 篇文献符合综述的纳入标准。在过去的十年中,因出血导致的死亡人数有所减少(25-15%)。未发现死亡发生率和模式有明显变化。创伤后死亡的主要原因仍然是中枢神经系统(CNS)损伤(21.6-71.5%),其次是出血(12.5-26.6%),而败血症(3.1-17%)和多器官衰竭(MOF)(1.6-9%)仍然是晚期死亡的主要原因。
比较过去三十年的手稿发现,因出血导致的死亡率有所降低。其他死因的发生率似乎没有变化。这些改进可能归因于多层 CT 的可用性、ATLS 概念的实施和紧急救援的后勤保障的发展。