Tandiono Theodore, Mintarjo Jessica Amelinda, Nugroho Nunung
Department of Physical Medicine and Rehabilitation, Primasatya Husada Citra Hospital, Surabaya, IDN.
Cureus. 2025 May 14;17(5):e84138. doi: 10.7759/cureus.84138. eCollection 2025 May.
Nonunion fractures, especially of the femur, pose a considerable difficulty in orthopedic management due to their propensity to result in enduring physical disability and psychological complications. Conventional surgical procedures, although efficacious, may entail difficulties and have a reduced success rate for atrophic nonunions. Extracorporeal shockwave therapy (ESWT) has arisen as a viable non-invasive option, facilitating bone regeneration via many biological mechanisms. This case report describes the management of a 40-year-old male patient with a distal-third open femoral fracture resulting from a motor vehicle accident. Despite receiving open reduction internal fixation and an extensive rehabilitation regimen, the patient had little callus development after six months. ESWT was commenced once weekly for 23 weeks, combined with ultrasonic low-intensity pulsed ultrasound (LIPUS) therapy and leg extension exercises. The patient had full callus formation on the femur and made a full recovery. The comprehensive literature evaluation demonstrates that ESWT can achieve a healing rate of around 73% for nonunion femoral fractures. The therapy's effectiveness is due to its capacity to induce osteogenic responses, promote osteoblast development, and suppress osteoclast production. This non-invasive method diminishes the necessity for supplementary surgical interventions and related complications. Additional research is required to develop standardized methods and refine therapy parameters, guaranteeing consistent and dependable results across various patient groups.
骨不连骨折,尤其是股骨骨折,因其易导致长期身体残疾和心理并发症,给骨科治疗带来了相当大的困难。传统外科手术虽然有效,但可能存在困难,且对于萎缩性骨不连的成功率较低。体外冲击波疗法(ESWT)已成为一种可行的非侵入性选择,通过多种生物学机制促进骨再生。本病例报告描述了一名40岁男性患者的治疗情况,该患者因机动车事故导致股骨远端三分之一开放性骨折。尽管接受了切开复位内固定和广泛的康复方案,但患者在六个月后骨痂形成很少。ESWT每周进行一次,共进行23周,同时结合超声低强度脉冲超声(LIPUS)治疗和腿部伸展运动。患者股骨完全形成骨痂并完全康复。综合文献评估表明,ESWT对股骨骨不连的愈合率可达73%左右。该疗法的有效性在于其能够诱导成骨反应、促进成骨细胞发育并抑制破骨细胞生成。这种非侵入性方法减少了额外手术干预和相关并发症的必要性。需要进一步研究以制定标准化方法并优化治疗参数,确保在不同患者群体中获得一致且可靠的结果。