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Effects on blood pressure, glucose, and lipid levels of a high-monounsaturated fat diet compared with a high-carbohydrate diet in NIDDM subjects.与高碳水化合物饮食相比，高单不饱和脂肪饮食对非胰岛素依赖型糖尿病（NIDDM）患者血压、血糖和血脂水平的影响。
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本文引用的文献

1
Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada. Introduction.加拿大糖尿病协会2013年加拿大糖尿病预防与管理临床实践指南。引言。
Can J Diabetes. 2013 Apr;37 Suppl 1:S1-3. doi: 10.1016/j.jcjd.2013.01.009. Epub 2013 Mar 26.
2
Association of diet with glycated hemoglobin during intensive treatment of type 1 diabetes in the Diabetes Control and Complications Trial.在糖尿病控制与并发症试验中1型糖尿病强化治疗期间饮食与糖化血红蛋白的关联
Am J Clin Nutr. 2009 Feb;89(2):518-24. doi: 10.3945/ajcn.2008.26498. Epub 2008 Dec 23.
3
Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association.糖尿病的营养建议与干预：美国糖尿病协会立场声明
Diabetes Care. 2008 Jan;31 Suppl 1:S61-78. doi: 10.2337/dc08-S061.
4
Intake of phenol-rich virgin olive oil improves the postprandial prothrombotic profile in hypercholesterolemic patients.摄入富含酚类的初榨橄榄油可改善高胆固醇血症患者的餐后血栓形成倾向。
Am J Clin Nutr. 2007 Aug;86(2):341-6. doi: 10.1093/ajcn/86.2.341.
5
Effect on 24-h energy expenditure of a moderate-fat diet high in monounsaturated fatty acids compared with that of a low-fat, carbohydrate-rich diet: a 6-mo controlled dietary intervention trial.与低脂、高碳水化合物饮食相比，富含单不饱和脂肪酸的适度脂肪饮食对24小时能量消耗的影响：一项为期6个月的对照饮食干预试验。
Am J Clin Nutr. 2007 Apr;85(4):1014-22. doi: 10.1093/ajcn/85.4.1014.
6
Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes.脂肪对2型糖尿病患者碳水化合物餐后胃排空以及血糖、胰岛素和肠促胰岛素反应的影响。
J Clin Endocrinol Metab. 2006 Jun;91(6):2062-7. doi: 10.1210/jc.2005-2644. Epub 2006 Mar 14.
7
Mediterranean diet and cardiovascular health.地中海饮食与心血管健康。
Ann N Y Acad Sci. 2005 Nov;1056:253-60. doi: 10.1196/annals.1352.012.
8
Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial.地中海式饮食对代谢综合征患者内皮功能障碍及血管炎症标志物的影响：一项随机试验。
JAMA. 2004 Sep 22;292(12):1440-6. doi: 10.1001/jama.292.12.1440.
9
A high carbohydrate versus a high monounsaturated fatty acid diet lowers the atherogenic potential of big VLDL particles in patients with type 1 diabetes.与高单不饱和脂肪酸饮食相比，高碳水化合物饮食可降低1型糖尿病患者大极低密度脂蛋白颗粒的致动脉粥样硬化潜力。
J Nutr. 2000 Oct;130(10):2503-7. doi: 10.1093/jn/130.10.2503.
10
The post-prandial state and cardiovascular disease: relevance to diabetes mellitus.餐后状态与心血管疾病：与糖尿病的相关性。
Diabetes Metab Res Rev. 2000 Mar-Apr;16(2):125-32. doi: 10.1002/(sici)1520-7560(200003/04)16:2<125::aid-dmrr90>3.0.co;2-4.

高碳水化合物/低脂肪饮食与低碳水化合物/高单不饱和脂肪饮食对1型糖尿病患者餐后甘油三酯浓度及其他心血管危险因素的影响。

Effects of a diet higher in carbohydrate/lower in fat versus lower in carbohydrate/higher in monounsaturated fat on postmeal triglyceride concentrations and other cardiovascular risk factors in type 1 diabetes.

作者信息

Strychar Irene, Cohn Jeffrey S, Renier Geneviève, Rivard Michèle, Aris-Jilwan Nahla, Beauregard Hugues, Meltzer Sara, Bélanger André, Dumas Richard, Ishac Alain, Radwan Farouk, Yale Jean-François

机构信息

Research Center of the University of Montreal Hospital Center, Montreal, Quebec, Canada.

出版信息

Diabetes Care. 2009 Sep;32(9):1597-9. doi: 10.2337/dc08-2322. Epub 2009 Jun 18.

DOI:10.2337/dc08-2322
PMID:19542011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2732152/
Abstract

OBJECTIVE

To compare the effects of a eucaloric diet higher in carbohydrate/lower in fat versus lower in carbohydrate/higher in monounsaturated fat on postmeal triglyceride (TG) concentrations and other cardiovascular disease risk factors in nonobese subjects with type 1 diabetes and in good glycemic control.

RESEARCH DESIGN AND METHODS

In a parallel group design study, 30 subjects were randomly assigned and completed one of the two eucaloric diets. Assessments included: BMI, blood pressure, A1C, plasma lipids, and markers of oxidation, thrombosis, and inflammation. At 6 months, subjects were hospitalized for 24 h to measure plasma TG excursions.

RESULTS

There were no significant differences between groups other than decreased plasminogen activator inhibitor 1 (PAI-1) levels and weight gain in the lower-carbohydrate/higher-monounsaturated fat group. During the 24-h testing, the lower-carbohydrate/higher-monounsaturated fat group had a lower plasma TG profile.

CONCLUSIONS

A diet lower in carbohydrate/higher in monounsaturated fat could offer an appropriate choice for nonobese type 1 diabetic individuals with good metabolic and weight control.

摘要

目的

比较碳水化合物含量较高/脂肪含量较低的等热量饮食与碳水化合物含量较低/单不饱和脂肪含量较高的等热量饮食对1型糖尿病且血糖控制良好的非肥胖受试者餐后甘油三酯（TG）浓度及其他心血管疾病风险因素的影响。

研究设计与方法

在一项平行组设计研究中，30名受试者被随机分配并完成两种等热量饮食中的一种。评估内容包括：体重指数、血压、糖化血红蛋白、血脂以及氧化、血栓形成和炎症标志物。6个月时，受试者住院24小时以测量血浆TG波动情况。

结果

除了碳水化合物含量较低/单不饱和脂肪含量较高组的纤溶酶原激活物抑制剂1（PAI-1）水平降低和体重增加外，两组之间无显著差异。在24小时测试期间，碳水化合物含量较低/单不饱和脂肪含量较高组的血浆TG水平较低。

结论

对于代谢和体重控制良好的非肥胖1型糖尿病患者，碳水化合物含量较低/单不饱和脂肪含量较高的饮食可能是一种合适的选择。