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英国肾脏注册机构第11次年度报告(2008年12月):第3章 2007年英国终末期肾病发病率:全国及特定中心分析

UK Renal Registry 11th Annual Report (December 2008): Chapter 3 ESRD incident rates in 2007 in the UK: national and centre-specific analyses.

作者信息

Farrington Ken, Udayaraj Udaya, Gilg Julie, Feehally John

机构信息

Lister Hospital, Stevenage, UK.

出版信息

Nephron Clin Pract. 2009;111 Suppl 1:c13-41. doi: 10.1159/000209992. Epub 2009 Mar 26.

Abstract

INTRODUCTION

This chapter describes the characteristics of adult patients starting renal replacement therapy (RRT) in the UK in 2007 and the acceptance rate for RRT in Primary Care Trusts (PCT) or equivalent Health Authority (HA) areas in the UK.

METHODS

The basic demographics are reported for all UK centres and clinical characteristics of patients starting RRT from all except 1 centre in the UK. Late presentation, defined as time between first being seen by a nephrologist and start of RRT being <90 days was also studied. Age and gender standardised ratios for acceptance rate in PCTs or equivalent HAs were calculated.

RESULTS

In 2007, the acceptance rate in the UK was 109 per million population (pmp) compared to 111 pmp in 2006. Acceptance rates in England (107 pmp), Scotland (108 pmp) and Northern Ireland (105 pmp) have fallen slightly, whilst that in Wales (140 pmp) has risen. There were wide variations between PCTs/HAs with respect to the standardised ratios which were lower in more PCTs in the North West and South East of England and higher in London, the West Midlands and Wales. The median age of all incident patients was 64.1 years and for non-Whites 57.1 years. There was an excess of males in all age groups starting RRT and nearly 80% of patients were reported to be White. Diabetic renal disease remained the single most common cause of renal failure (21.9%). By 90 days, 67.4% of patients were on haemodialysis, 21.3% on peritoneal dialysis, 5.2% had had a transplant and 6.1% had died or had stopped treatment. The incidence of late presentation in those centres supplying adequate data was 21%.

CONCLUSIONS

The acceptance rate has fallen in England, Northern Ireland and Scotland but continues to rise in Wales with wide variations in acceptance rate between PCTs/HAs.

摘要

引言

本章描述了2007年在英国开始接受肾脏替代治疗(RRT)的成年患者的特征,以及英国初级保健信托基金(PCT)或同等卫生当局(HA)地区的RRT接受率。

方法

报告了英国所有中心的基本人口统计学数据以及英国除1个中心外所有开始接受RRT治疗患者的临床特征。还研究了延迟就诊情况,即从首次就诊于肾病科医生到开始RRT治疗的时间<90天。计算了PCT或同等HA地区接受率的年龄和性别标准化比率。

结果

2007年,英国的接受率为每百万人口109例(pmp),而2006年为111 pmp。英格兰(107 pmp)、苏格兰(108 pmp)和北爱尔兰(105 pmp)的接受率略有下降,而威尔士(140 pmp)的接受率有所上升。PCT/HA之间的标准化比率存在很大差异,在英格兰西北部和东南部的更多PCT中较低,而在伦敦、西米德兰兹和威尔士较高。所有新发病例患者的中位年龄为64.1岁,非白人患者为57.1岁。开始接受RRT治疗的所有年龄组中男性均占多数,据报告近80%的患者为白人。糖尿病肾病仍然是肾衰竭的最常见单一原因(21.9%)。到90天时,67.4%的患者接受血液透析,21.3%接受腹膜透析,5.2%已接受移植,6.1%已死亡或停止治疗。提供充分数据的那些中心的延迟就诊发生率为21%。

结论

英格兰、北爱尔兰和苏格兰的接受率有所下降,但威尔士的接受率继续上升,PCT/HA之间的接受率存在很大差异。

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