UK Renal Registry, Bristol, UK.
Nephron Clin Pract. 2012;120 Suppl 1:c1-27. doi: 10.1159/000342843. Epub 2012 Sep 1.
This chapter describes the characteristics of adult patients starting renal replacement therapy (RRT) in the UK in 2010 and the incidence rates for RRT in Primary Care Trusts and Health Boards (PCT/HBs) in the UK.
The basic demographics and clinical characteristics are reported on patients starting RRT from all UK renal centres. Presentation time, defined as time between first being seen by a nephrologist and start of RRT, was also studied. Age and gender standardised ratios for incidence rates in PCT/HBs were also calculated.
In 2010, the incidence rates in the UK and England were similar to 2009 at 107 per million population (pmp). The incidence rate fell in Scotland (from 104 pmp to 95 pmp), increased in Northern Ireland (from 88 pmp to 101 pmp) and Wales (from 120 pmp to 128 pmp). There were wide variations between PCT/HBs in standardised incidence ratios. The median age of all incident patients was 64.9 years (IQR 51.0, 75.2). For transplant centres this was 63.1 years (IQR 49.7, 74.2) and for non-transplanting centres 66.5 years (IQR 52.9, 76.0). The median age for non-Whites was 57.1 years. Diabetic renal disease remained the single most common cause of renal failure (24%). By 90 days, 68.3% of patients were on haemodialysis, 18.1% on peritoneal dialysis, 7.7% had had a transplant and 5.9% had died or stopped treatment. The mean eGFR at the start of RRT was 8.7 ml/ min/1.73 m(2) which was similar to the previous three years. Late presentation (<90 days) fell from 28.2% in 2005 to 20.6% in 2010. There was no relationship between social deprivation and presentation pattern.
Incidence rates have plateaued in England over the last five years. They have fallen in Scotland and fallen and then risen again in Northern Ireland and Wales. Wales continued to have the highest incidence rate of the countries making up the UK.
本章描述了 2010 年英国开始接受肾脏替代治疗（RRT）的成年患者的特征，以及英国初级保健信托和卫生委员会（PCT/HB）的 RRT 发病率。
报告了所有英国肾脏中心开始接受 RRT 的患者的基本人口统计学和临床特征。还研究了开始 RRT 前的就诊时间，定义为首次接受肾脏病医生就诊与开始 RRT 之间的时间。还计算了 PCT/HB 中发病率的年龄和性别标准化比值。
2010 年，英国和英格兰的发病率与 2009 年相似，为每百万人口 107 例（pmp）。苏格兰的发病率下降（从 104 pmp 降至 95 pmp），北爱尔兰（从 88 pmp 增至 101 pmp）和威尔士（从 120 pmp 增至 128 pmp）的发病率上升。PCT/HB 之间的标准化发病率差异很大。所有新发病例的中位年龄为 64.9 岁（IQR 51.0，75.2）。对于移植中心，这一年龄为 63.1 岁（IQR 49.7，74.2），而非移植中心为 66.5 岁（IQR 52.9，76.0）。非白人的中位年龄为 57.1 岁。糖尿病肾病仍然是肾衰竭的最常见原因（24％）。90 天内，68.3％的患者接受血液透析，18.1％接受腹膜透析，7.7％接受了移植，5.9％死亡或停止治疗。开始 RRT 时的平均 eGFR 为 8.7 ml/min/1.73 m(2)，与前三年相似。晚期表现（<90 天）从 2005 年的 28.2％降至 2010 年的 20.6％。社会贫困与表现模式之间没有关系。
英格兰的发病率在过去五年中已趋于平稳。苏格兰的发病率下降，北爱尔兰和威尔士的发病率先下降后上升。威尔士继续保持英国各组成国家中发病率最高的国家。
