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肝十二指肠吻合术是活体供肝肝移植中胆管重建的一种替代Roux-en-Y肝空肠吻合术的方法。

Hepaticoduodenostomy is an alternative to Roux-en-Y hepaticojejunostomy for biliary reconstruction in live donor liver transplantation.

作者信息

Campsen Jeffrey, Zimmerman Michael A, Mandell Mercedes Susan, Wachs Michael, Bak Tom, Forman Lisa, Steinberg Tracy, Kam Igal

机构信息

Division of Transplant Surgery, University of Colorado Health Sciences Center, Aurora, CO, USA.

出版信息

Transplantation. 2009 Jun 27;87(12):1842-5. doi: 10.1097/TP.0b013e3181a6bb5e.

Abstract

INTRODUCTION

A Roux-en-Y hepaticojejunostomy (HJ) is usually performed during live donor liver transplantation (LDLT) when a duct-to-duct reconstruction is not possible. However, direct anastomosis of the bile duct to the duodenum (hepaticoduodenostomy [HD]) is an alternative technique for biliary repair that has been previously used for conventional biliary surgery and at our center for cadaveric liver transplant. We provide the first evidence that HD is an alternative technique for biliary reconstruction in LDLT.

METHODS

We performed a total of 71 LDLT between 2002 and 2008. An end-to-end anastomosis was used in 30 patients. Forty-one patients had a biliary enteric anastomosis in which seven were reconstructed with an HD. Accessory ducts were fashioned into a common duct or implanted into the duodenum separately.

RESULTS

There were no patient deaths or retransplants in a follow-up period that ranged from 90 to 771 days after surgery. One patient was diagnosed with cholangitis that responded to intravenous antibiotics and removal of the stent by endoscopy.

CONCLUSIONS

This preliminary case series suggests that that HD is a feasible alternative to HJ biliary anastomosis when a duct-to-duct anastomosis cannot be performed. HD offers the possible advantage of simple postoperative access to the biliary system by endoscopy and avoids complications caused by HJ bowel anastomosis.

摘要

引言

当无法进行胆管对胆管重建时,通常在活体肝移植(LDLT)中施行 Roux-en-Y 肝空肠吻合术(HJ)。然而,胆管与十二指肠直接吻合(肝十二指肠吻合术[HD])是一种胆道修复的替代技术,此前已用于传统胆道手术,在我们中心也用于尸体肝移植。我们提供了首个证据,表明 HD 是 LDLT 中胆道重建的替代技术。

方法

2002 年至 2008 年期间,我们共进行了 71 例 LDLT。30 例患者采用端端吻合。41 例患者进行了胆肠吻合,其中 7 例采用 HD 重建。附属胆管被制成胆总管或分别植入十二指肠。

结果

术后 90 至 771 天的随访期内,无患者死亡或再次移植。1 例患者被诊断为胆管炎,经静脉使用抗生素及内镜下取出支架后病情缓解。

结论

这个初步的病例系列表明,当无法进行胆管对胆管吻合时,HD 是 HJ 胆道吻合的可行替代方法。HD 的可能优势在于术后可通过内镜简单地进入胆道系统,并避免了 HJ 肠吻合引起的并发症。

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