Valdivia C Gonzalo, Caussade L Solange, Navarro M Héctor, Cerda L Jaime, Pérez B Enrique, Aquevedo S Andrés, Sánchez D Ignacio
Departamento de Salud Pública, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago de Chile.
Rev Med Chil. 2009 Feb;137(2):215-25. Epub 2009 Jun 10.
Asthma prevalence is increasing worldwide, especially in developing countries.
To determine the prevalence of asthma diagnosis and related symptoms in children, its changes during a 6-year period and the influence exerted by socioeconomic status.
Cross-sectional study conducted among school children of Santiago. A sample of 4,561 children aged 6-7 and 13-14 years attending public schools (central district, medium-low and low socioeconomic status) and private schools (eastern districts, high socioecomic status) were surveyed. Dependent variables were asthma diagnosis (AD), wheezing during the last 12 months (WHE12) and frequency of episodes of wheezing (FEW). Prevalence odds ratios were calculated using regression models, adjusted for several confounding variables.
AD prevalence for the group as a whole was higher in boys than in girls (13.2% and 10.8%, respectively p =0.016). Prevalence rate of AD was also higher for children aged 13-14 than 6-7 years (13.8% and 10.1%, respectively p <0.01). An inverse association was found between SES and WHE12. Higher maternal education level was associated with lower prevalence of WHE12 in both age groups and with lower prevalence of FEW in 6-7 year-old children. Paternal education level was positively associated with AD among younger children. At the central district, increasing trends of WHE12 and FEW prevalence were observed during 1994-2000 among 6-7 years children.
A significant association was observed between socioeconomic status, asthma diagnosis and symptoms in school children living in Santiago. Data support an increasing trend of asthma prevalence and severity among 6-7 year-old children during the period 1994-2000.
全球哮喘患病率正在上升,尤其是在发展中国家。
确定儿童哮喘诊断及相关症状的患病率、其在6年期间的变化以及社会经济地位所产生的影响。
在圣地亚哥的学童中开展横断面研究。对4561名6至7岁以及13至14岁的儿童进行了调查,这些儿童就读于公立学校(中心区,社会经济地位中低和低)和私立学校(东部地区,社会经济地位高)。因变量为哮喘诊断(AD)、过去12个月内的喘息(WHE12)以及喘息发作频率(FEW)。使用回归模型计算患病率比值比,并对多个混杂变量进行了调整。
总体而言,男孩的AD患病率高于女孩(分别为13.2%和10.8%,p = 0.016)。13至14岁儿童的AD患病率也高于6至7岁儿童(分别为13.8%和10.1%,p < 0.01)。SES与WHE12之间存在负相关。较高的母亲教育水平与两个年龄组中WHE12的较低患病率以及6至7岁儿童中FEW的较低患病率相关。父亲教育水平与年幼儿童的AD呈正相关。在中心区,1994 - 2000年期间6至7岁儿童中WHE12和FEW患病率呈上升趋势。
在居住于圣地亚哥的学童中,观察到社会经济地位、哮喘诊断和症状之间存在显著关联。数据支持1994 - 2000年期间6至7岁儿童哮喘患病率和严重程度呈上升趋势。