Division of Infectious Disease, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Curr Infect Dis Rep. 2009 Jul;11(4):311-8. doi: 10.1007/s11908-009-0046-y.
The improved efficacy and safety of antiretroviral agents have fundamentally changed the face of HIV infection. Advances in antiretroviral therapy have dramatically improved the prognosis of HIV infection, which is now on a par with other chronic illnesses. This article addresses the optimal timing of antiretroviral therapy initiation and the optimal drug choices for initial regimens, with a focus on recent data and published guidelines issued by the US Department of Health and Human Services and the International AIDS Society-USA.
抗逆转录病毒药物疗效的提高和安全性的改善，从根本上改变了 HIV 感染的面貌。抗逆转录病毒治疗的进步显著改善了 HIV 感染的预后，使其现在与其他慢性疾病相当。本文讨论了抗逆转录病毒治疗开始的最佳时机和初始方案的最佳药物选择，重点关注了美国卫生与公众服务部和国际艾滋病协会-美国发布的最新数据和已发表的指南。
