Tu Jack V, Nardi Lorelei, Fang Jiming, Liu Juan, Khalid Laila, Johansen Helen
Institute for Clinical Evaluative Sciences, Toronto, Ont.
CMAJ. 2009 Jun 23;180(13):E118-25. doi: 10.1503/cmaj.081197.
Rates of death from cardiovascular and cerebrovascular diseases have been steadily declining over the past few decades. Whether such declines are occurring to a similar degree for common disorders such as acute myocardial infarction, heart failure and stroke is uncertain. We examined recent national trends in mortality and rates of hospital admission for these 3 conditions.
We analyzed mortality data from Statistic Canada's Canadian Mortality Database and data on hospital admissions from the Canadian Institute for Health Information's Hospital Morbidity Database for the period 1994-2004. We determined age- and sex-standardized rates of death and hospital admissions per 100,000 population aged 20 years and over as well as in-hospital case-fatality rates.
The overall age- and sex-standardized rate of death from cardiovascular disease in Canada declined 30.0%, from 360.6 per 100,000 in 1994 to 252.5 per 100 000 in 2004. During the same period, the rate fell 38.1% for acute myocardial infarction, 23.5% for heart failure and 28.2% for stroke, with improvements observed across most age and sex groups. The age- and sex-standardized rate of hospital admissions decreased 27.6% for stroke and 27.2% for heart failure. The rate for acute myocardial infarction fell only 9.2%. In contrast, the relative decline in the in-hospital case-fatality rate was greatest for acute myocardial infarction (33.1%; p < 0.001). Much smaller relative improvements in case-fatality rates were noted for heart failure (8.1%) and stroke (8.9%).
The rates of death and hospital admissions for acute myocardial infarction, heart failure and stroke in Canada changed at different rates over the 10-year study period. Awareness of these trends may guide future efforts for health promotion and health care planning and help to determine priorities for research and treatment.
在过去几十年中,心血管和脑血管疾病的死亡率一直在稳步下降。对于急性心肌梗死、心力衰竭和中风等常见疾病,这种下降程度是否相似尚不确定。我们研究了这三种疾病近期的全国死亡率趋势和住院率。
我们分析了加拿大统计局加拿大死亡率数据库中的死亡率数据,以及加拿大卫生信息研究所医院发病率数据库中1994年至2004年期间的住院数据。我们确定了每10万20岁及以上人口的年龄和性别标准化死亡率和住院率,以及住院病死率。
加拿大心血管疾病的总体年龄和性别标准化死亡率下降了30.0%,从1994年的每10万人360.6例降至2004年的每10万人252.5例。在同一时期,急性心肌梗死的死亡率下降了38.1%,心力衰竭下降了23.5%,中风下降了28.2%,在大多数年龄和性别组中都有改善。中风的年龄和性别标准化住院率下降了27.