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喜马拉雅山区一个村庄的室内污染与呼吸道疾病

Domestic pollution and respiratory illness in a Himalayan village.

作者信息

Norboo T, Yahya M, Bruce N G, Heady J A, Ball K P

机构信息

SNM Hospital, Leh, Ladakh, India.

出版信息

Int J Epidemiol. 1991 Sep;20(3):749-57. doi: 10.1093/ije/20.3.749.

DOI:10.1093/ije/20.3.749
PMID:1955261
Abstract

Summer and winter surveys of a village in Ladakh have been used to study respiratory illness and domestic pollution from fires in an arid high altitude region of northern India. The prevalence of chronic cough with chronic phlegm rose steeply with age, and was greater among women than men. The percentage of villagers with a forced expiratory volume in one second/forced vital capacity (FEV1/FVC) ratio of less than 65% also rose with age, to include 24% of men and 32% of women over 50 years in the summer survey. Lung function was significantly worse in those reporting chronic cough, independently of age and sex (p less than 0.001). Carbon monoxide (CO) measurements were used to assess domestic pollution from fires. Amongst the small minority of smokers (all men) CO in exhaled air was higher than in non-smoking men. In non-smoking men and the women, levels of exhaled CO were very significantly higher in winter than in summer, as were the levels of CO measured in the houses. There was a fall in FEV1 (but not FVC) between summer and winter (p less than 0.0001), and an association was found between individual change from summer to winter in exhaled air CO and the individual change in FEV1 (p less than 0.01). A significant negative association was found between the winter value of CO in exhaled air and FEV1/FVC ratio in women (p less than 0.05), although a similar association in men was non-significant. No significant associations were found between winter pollution levels and the presence of chronic symptoms.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

印度北部干旱高海拔地区一个村庄的夏季和冬季调查被用于研究呼吸系统疾病以及火灾造成的室内污染。伴有慢性咳痰的慢性咳嗽患病率随年龄急剧上升,且女性高于男性。一秒用力呼气量/用力肺活量(FEV1/FVC)比值低于65%的村民比例也随年龄上升,在夏季调查中,50岁以上男性中有24%、女性中有32%属于此情况。报告有慢性咳嗽的人群,其肺功能明显更差,与年龄和性别无关(p<0.001)。一氧化碳(CO)测量用于评估火灾造成的室内污染。在少数吸烟者(均为男性)中,呼出气体中的CO高于不吸烟男性。在不吸烟男性和女性中,呼出CO水平在冬季显著高于夏季,房屋内测量的CO水平也是如此。夏季到冬季期间,FEV1(但FVC未出现此情况)有所下降(p<0.0001),并且发现呼出气体CO从夏季到冬季的个体变化与FEV1的个体变化之间存在关联(p<0.01)。虽然男性中类似关联不显著,但发现女性呼出气体中CO的冬季值与FEV1/FVC比值之间存在显著负相关(p<0.05)。未发现冬季污染水平与慢性症状的存在之间存在显著关联。(摘要截选至250词)

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