新南威尔士州麻疹接触者预防措施的有效性。
The effectiveness of prophylaxis for measles contacts in NSW.
作者信息
Sheppeard Vicky, Forssman Bradley, Ferson Mark J, Moreira Conrad, Campbell-Lloyd Sue, Dwyer Dominic E, McAnulty Jeremy M
机构信息
Centre for Health Protection, NSW Department of Health, Australia.
出版信息
N S W Public Health Bull. 2009 May-Jun;20(5-6):81-5. doi: 10.1071/NB08014.
OBJECTIVES
As international estimates of the effectiveness of post-exposure prophylaxis of measles vary, we sought to determine the effectiveness of post-exposure prophylaxis with either vaccine or immunoglobulin in susceptible persons with known measles contact.
METHODS
Data were obtained on all cases of measles notified in NSW between 1 March and 31 May 2006 and their contacts. The effectiveness of prophylaxis was calculated using the cohort method.
RESULTS
During March to May 2006, 57 cases of measles were notified and 1760 measles contacts were identified, of which 553 were classified as susceptible. The calculated effectiveness of post-exposure prophylaxis with vaccine or immunoglobulin in preventing measles was 83.3% (95% CI: 27-96%).
CONCLUSION
Post-exposure immunisation remains an effective tool for preventing secondary cases of measles.
目的
由于国际上对麻疹暴露后预防效果的评估存在差异，我们试图确定在已知接触麻疹的易感人群中，使用疫苗或免疫球蛋白进行暴露后预防的效果。
方法
获取了2006年3月1日至5月31日新南威尔士州报告的所有麻疹病例及其接触者的数据。采用队列研究方法计算预防效果。
结果
2006年3月至5月期间，报告了57例麻疹病例，确定了1760名麻疹接触者，其中553人被归类为易感人群。计算得出，使用疫苗或免疫球蛋白进行暴露后预防麻疹的效果为83.3%（95%置信区间：27 - 96%）。
结论
暴露后免疫仍然是预防麻疹二代病例的有效手段。
Zotero 插件