下肢一种罕见的毛囊皮脂腺囊性错构瘤。
An uncommon folliculosebaceous cystic hamartoma on the lower extremity.
作者信息
Emsen Ilteris Murat, Livaoglu Ayten
机构信息
Department of Plastic and Reconstructive Surgery, Numune State Hospital, Erzurum, Turkey.
出版信息
Can J Plast Surg. 2007 Winter;15(4):231-3. doi: 10.1177/229255030701500402.
BACKGROUND
Folliculosebaceous cystic hamartomas (FSCH) are a recently recognized cutaneous hamartoma comprised of follicular, sebaceous and mesenchymal elements. Only nine cases have been previously reported. The authors present a case of FSCH on the lower extremity in addition to a literature review.
OBJECTIVE
To further characterize the clinical, histological and immunohistological features of FSCH.
METHODS
The clinical, histological and immunohistological features of FSCH were evaluated and the literature reviewed.
RESULTS
This lesion uncommonly presents as exophytic papules or nodules on the leg, and most commonly presents on the central part of the face. Clinical differential diagnoses included nevus, neurofibroma and adnexal tumour. The diagnostic microscopic features of infundibular cystic structures with attached sebaceous glands and characteristic stroma were present in all lesions. Many of the stromal spindle cells were CD34-positive.
CONCLUSION
The FSCH is a recently recognized hamartoma comprised of follicular, sebaceous and mesenchymal elements. Although reported only rarely, its incidence is likely much higher. In the present patient, the FSCH was located in femoral region, which is very rare.
背景
毛囊皮脂腺囊性错构瘤（FSCH）是一种最近才被认识的皮肤错构瘤，由毛囊、皮脂腺和间充质成分组成。此前仅有9例报告。作者报告了1例发生于下肢的FSCH病例，并进行文献复习。
目的
进一步明确FSCH的临床、组织学和免疫组织学特征。
方法
对FSCH的临床、组织学和免疫组织学特征进行评估，并复习文献。
结果
该病变罕见地表现为腿部的外生性丘疹或结节，最常见于面部中央。临床鉴别诊断包括痣、神经纤维瘤和附属器肿瘤。所有病变均具有漏斗状囊性结构、附着的皮脂腺和特征性间质等诊断性显微镜特征。许多间质梭形细胞CD34呈阳性。
结论
FSCH是一种最近才被认识的由毛囊、皮脂腺和间充质成分组成的错构瘤。虽然报告很少，但发病率可能要高得多。在本例患者中，FSCH位于股骨区域，非常罕见。
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