Department of Breast Oncology, Saitama International Medical Center, Saitama Medical University, 1397-1 Yaname, Hidaka, Saitama, Japan.
Breast Cancer. 2011 Apr;18(2):141-4. doi: 10.1007/s12282-009-0125-9. Epub 2009 Jun 24.
Recent advanced imaging modalities such as positron emission tomography (PET) detect malignancies using 2-[18F]-fluoro-2-deoxy-D: -glucose (18-FDG) with high accuracy, and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false-positive metastatic lymph nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography. PET/CT revealed high uptake of 18-FDG in the tumors. To investigate the proposed recurrence and to re-evaluate the biology of the recurrent tumors, a tumor was removed from the brachial plexus of the patient. Histological findings revealed it to be a schwannoma. All imaging modalities including PET/CT failed to distinguish benign tumors from metastatic lymph nodes in the brachial plexus. After resection of the schwannomas, the patient complained of a slight motor disorder of the second finger on the right hand. Hence, it is important to consider a false-positive case of lymph node metastasis in a breast cancer patient following mastectomy.
最近的先进成像方式，如正电子发射断层扫描（PET），使用 2-[18F]-氟-2-脱氧-D: -葡萄糖（18-FDG）以高精度检测恶性肿瘤，它们有助于做出关于诊断、分期、复发和治疗反应的决策。在这里，我们报告了一例假阳性转移性淋巴结的病例，该病例是在一名接受乳房切除术的 48 岁乳腺癌患者中通过 PET/CT 和超声诊断的。肿瘤呈椭圆形，类似于淋巴结，超声检查发现。PET/CT 显示肿瘤中 18-FDG 的摄取量很高。为了研究拟议的复发并重新评估复发性肿瘤的生物学特性，从患者的臂丛中切除了一个肿瘤。组织学发现它是一个神经鞘瘤。所有的成像方式，包括 PET/CT，都无法区分臂丛中的良性肿瘤和转移性淋巴结。神经鞘瘤切除后，患者抱怨右手第二指有轻微运动障碍。因此，对于乳房切除术后的乳腺癌患者，假阳性淋巴结转移的情况需要考虑。
