Ugajin Motoi, Yamashita Masakatsu, Kani Hisanori
Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, Kasugai City, Japan.
Department of Respiratory Medicine and Allergology, Aichi Medical University, Nagakute City, Japan.
Eur J Case Rep Intern Med. 2023 Aug 31;10(10):004048. doi: 10.12890/2023_004048. eCollection 2023.
A 69-year-old man was diagnosed with lung adenocarcinoma with metastasis because two masses in the right intercostal space and right back muscle showed high accumulation on positron emission tomography (PET). The 6-month treatment with osimertinib significantly reduced his lung lesion, but no changes were observed in the metastatic lesions. Needle biopsy revealed that the lesion in the right back muscle was a schwannoma. Surgical resection revealed that the right intercostal lesion was also a schwannoma; subsequently, a right upper lobectomy was performed. The patient was finally diagnosed with lung adenocarcinoma without metastasis. High accumulations of lesions observed on PET may indicate schwannomas.
Benign schwannomas could show high accumulations on positron emission tomography.Accurate diagnosis of schwannoma using only images is quite challenging.Histological examinations should be considered when asymptomatic lesions are suspected to be metastases.
一名69岁男性被诊断为伴有转移的肺腺癌,因为右肋间间隙和右背部肌肉的两个肿块在正电子发射断层扫描(PET)上显示高摄取。使用奥希替尼进行的6个月治疗显著缩小了他的肺部病变,但转移病灶未见变化。针吸活检显示右背部肌肉的病变为神经鞘瘤。手术切除显示右肋间病变也是神经鞘瘤;随后进行了右上肺叶切除术。该患者最终被诊断为无转移的肺腺癌。PET上观察到的病变高摄取可能提示神经鞘瘤。
良性神经鞘瘤在正电子发射断层扫描上可能显示高摄取。仅通过图像准确诊断神经鞘瘤颇具挑战性。当无症状病变疑似为转移灶时,应考虑进行组织学检查。