Research Centre for Prevention and Health, Glostrup University Hospital, Building 84/85, DK-2600 Glostrup, Denmark.
Prev Med. 2009 Aug-Sep;49(2-3):115-21. doi: 10.1016/j.ypmed.2009.06.007. Epub 2009 Jun 23.
To investigate the effect of screening and five years of multi-factorial lifestyle intervention on changes in alcohol intake in a general population.
The study was a pre-randomized intervention study on lifestyle, Inter99 (1999-2006), Copenhagen, Denmark. Participants in the intervention group (n=6 091) had at baseline a medical health examination and a face-to-face lifestyle counselling. Individuals at high risk of ischemic heart disease were repeatedly offered both individual and group-based counselling. The control group (n=3 324) was followed by questionnaires. Alcohol intake was measured by questionnaires. Changes were analysed by multilevel analyses.
Binge drinking decreased both in men and women at three and five-year follow-ups (men: five-year: net-change:-0.13; p=0.03; women: five-year: net-change:-0.08; p=0.04). Furthermore, in women the ratio between wine and total alcohol was increased compared with the control group at five-year follow-up (net-change: 0.04; p<0.01). In men with a high intake of alcohol (>21 drinks per week) the effect on total alcohol intake was maintained at five-year follow-up (net-change: -3.7; p=0.01). No significant effects were found in women on total alcohol intake.
Multi-factorial lifestyle intervention, including low intensity alcohol intervention, improved long-term alcohol habits in a general population.
研究一般人群中筛查和五年多因素生活方式干预对饮酒量变化的影响。
本研究是一项关于生活方式的预随机干预研究，Inter99（1999-2006），丹麦哥本哈根。干预组（n=6091）的参与者在基线时有一次医疗健康检查和一次面对面的生活方式咨询。有缺血性心脏病高风险的个体反复获得个人和小组为基础的咨询。对照组（n=3324）通过问卷调查进行随访。饮酒量通过问卷调查进行测量。通过多层次分析对变化进行分析。
在男女三组和五年随访中，狂饮均减少（男性：五年：净变化-0.13；p=0.03；女性：五年：净变化-0.08；p=0.04）。此外，与对照组相比，女性在五年随访时葡萄酒和总酒精的比例增加（净变化：0.04；p<0.01）。对于高饮酒量（>21 杯/周）的男性，干预对总饮酒量的影响在五年随访时仍然存在（净变化：-3.7；p=0.01）。对于女性，总饮酒量没有发现显著影响。
包括低强度酒精干预在内的多因素生活方式干预改善了一般人群的长期饮酒习惯。
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