Department of Health Sciences, University of York, Heslington, York YO10 5DD, UK.
Trials. 2013 Apr 30;14:117. doi: 10.1186/1745-6215-14-117.
Alcohol misuse is a major cause of premature mortality and ill health. Although there is a high prevalence of alcohol problems among patients presenting to general hospital, many of these people are not help seekers and do not engage in specialist treatment. Hospital admission is an opportunity to steer people towards specialist treatment, which can reduce health-care utilization and costs to the public sector and produce substantial individual health and social benefits. Alcohol misuse is associated with other lifestyle problems, which are amenable to intervention. It has been suggested that the development of a healthy or balanced lifestyle is potentially beneficial for reducing or abstaining from alcohol use, and relapse prevention. The aim of the study is to test whether or not the offer of a choice of health-related lifestyle interventions is more acceptable, and therefore able to engage more problem drinkers in treatment, than an alcohol-focused intervention.
METHODS/DESIGN: This is a pragmatic, randomized, controlled, open pilot study in a UK general hospital setting with concurrent economic evaluation and a qualitative component. Potential participants are those admitted to hospital with a diagnosis likely to be responsive to addiction interventions who score equal to or more than 16 on the Alcohol Use Disorders Identification Test (AUDIT). The main purpose of this pilot study is to evaluate the acceptability of two sorts of interventions (healthy living related versus alcohol focused) to the participants and to assess the components and processes of the design. Qualitative research will be undertaken to explore acceptability and the impact of the approach, assessment, recruitment and intervention on trial participants and non-participants. The effectiveness of the two treatments will be compared at 6 months using AUDIT scores as the primary outcome measure. There will be additional economic, qualitative and secondary outcome measurements.
Development of the study was a collaboration between academics, commissioners and clinicians in general hospital and addiction services, made possible by the Collaboration in Leadership in Applied Health Research and Care (CLAHRC) program of research. CLAHRC was a necessary vehicle for overcoming the barriers to answering an important NHS question--how better to engage problem drinkers in a hospital setting.
ISRCTN47728072.
酗酒是导致早逝和健康状况不佳的主要原因之一。尽管在综合医院就诊的患者中，酒精问题的患病率很高，但其中许多人并非寻求帮助者，也不会接受专业治疗。住院是引导人们接受专业治疗的机会，可以减少公共部门的医疗保健利用和成本，并产生实质性的个人健康和社会效益。酗酒与其他生活方式问题有关，这些问题可以通过干预来解决。有人认为，养成健康或平衡的生活方式可能有助于减少或戒除酒精使用，以及预防复发。本研究的目的是测试提供一系列与健康相关的生活方式干预措施是否更受欢迎，从而能够让更多的问题饮酒者接受治疗，而不是专注于酒精的干预措施。
方法/设计：这是一项在英国综合医院环境中进行的实用、随机、对照、开放性试点研究，同时进行经济评估和定性部分。潜在的参与者是那些因可能对成瘾干预有反应而住院的人，他们的酒精使用障碍识别测试（AUDIT）得分等于或高于 16 分。这项试点研究的主要目的是评估两种干预措施（与健康生活相关的干预和专注于酒精的干预）对参与者的可接受性，并评估设计的组成部分和流程。将进行定性研究，以探讨方法、评估、招募和干预对试验参与者和非参与者的可接受性和影响。将使用 AUDIT 评分作为主要结果测量指标，在 6 个月时比较两种治疗方法的效果。还将进行额外的经济、定性和次要结果测量。
该研究的开展是学术界、决策者和综合医院及成瘾服务机构的临床医生之间的合作，这得益于合作领导力在应用健康研究和护理（CLAHRC）计划的研究。CLAHRC 是克服回答 NHS 重要问题的障碍的必要手段，即如何更好地让问题饮酒者在医院环境中接受治疗。
ISRCTN47728072。
