抗菌环D，L-α-糖肽
Antibacterial cyclic D,L-alpha-glycopeptides.
作者信息
Motiei Leila, Rahimipour Shai, Thayer Desiree A, Wong Chi-Huey, Ghadiri M Reza
机构信息
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
Chem Commun (Camb). 2009 Jul 7(25):3693-5. doi: 10.1039/b902455g. Epub 2009 May 29.
Abstract
We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic D,L-alpha-glycopeptides bearing d-glucosamine (GlcNH(2)), D-galactose (Gal), or D-mannose (Man) glycosyl side chains.
摘要
我们报告了带有D-葡萄糖胺（GlcNH₂）、D-半乳糖（Gal）或D-甘露糖（Man）糖基侧链的阳离子环D，L-α-糖肽的设计、合成、膜活性、生物物理特性及体外抗菌活性。
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