上半规管裂综合征（SCDS）患者的颈性前庭诱发肌源性电位（cVEMPs）
Cervical vestibular evoked myogenic potentials (cVEMPs) in patients with superior canal dehiscence syndrome (SCDS).
作者信息
Roditi Rachel E, Eppsteiner Robert W, Sauter Todd B, Lee Daniel J
机构信息
Department of Otolaryngology, University of Massachusetts Medical School, Worcester, MA, USA.
出版信息
Otolaryngol Head Neck Surg. 2009 Jul;141(1):24-8. doi: 10.1016/j.otohns.2009.03.012.
OBJECTIVE
To determine the usefulness of both amplitude and threshold data from tone-burst cervical vestibular evoked myogenic potential (cVEMP) testing for the evaluation of superior canal dehiscence syndrome (SCDS).
STUDY DESIGN
Case series with chart review.
SUBJECTS AND METHODS
Sixty-seven patients underwent cVEMP testing. We correlated mean tone burst cVEMP amplitude and threshold data with temporal bone CT findings. Patients were excluded for Ménière's disease, middle ear disease, or otologic surgery.
RESULTS
Superior canal dehiscence patients had higher mean cVEMP amplitudes (SCDS 173.8 microV vs non-SCDS 69.7 microV, P=0.031) and lower mean thresholds (SCDS 72.8 dB nHL vs non-SCDS 80.9 dB nHL) at 500 Hz.
CONCLUSION
Patients with SCDS have larger amplitudes and lower thresholds on cVEMP testing at 500 Hz. This study supports the utility of tone burst cVEMPs for the evaluation of SCDS and is one of few large single-center studies to establish normative data.
目的
确定短纯音刺激颈肌前庭诱发肌源性电位（cVEMP）测试中的波幅和阈值数据对评估半规管裂综合征（SCDS）的有用性。
研究设计
病例系列研究并进行图表回顾。
研究对象与方法
67例患者接受了cVEMP测试。我们将短纯音刺激cVEMP的平均波幅和阈值数据与颞骨CT结果进行了关联分析。排除患有梅尼埃病、中耳疾病或接受过耳科手术的患者。
结果
半规管裂患者在500Hz时的平均cVEMP波幅更高（SCDS组为173.8μV，非SCDS组为69.7μV，P = 0.031），平均阈值更低（SCDS组为72.8dB nHL，非SCDS组为80.9dB nHL）。
结论
SCDS患者在500Hz的cVEMP测试中波幅更大、阈值更低。本研究支持短纯音刺激cVEMP对SCDS评估的实用性，并且是为数不多的建立了正常数据的大型单中心研究之一。
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