Demir Emine, Afacan Nazife Nur, Celiker Metin, Celiker Fatma Beyazal, İnecikli Mehmet Fatih, Terzi Suat, Dursun Engin
Department of Otorhinolaryngology, Recep Tayyip Erdogan University Faculty of Medicine, Rize, Turkey.
Department of Radiology, Recep Tayyip Erdogan University Faculty of Medicine, Rize, Turkey.
Clin Exp Otorhinolaryngol. 2019 Aug;12(3):249-254. doi: 10.21053/ceo.2018.01137. Epub 2018 Nov 22.
We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD.
We compared the WBT data of patients clinically and radiologically diagnosed with SSCD in our hospital between 2013 and 2018 to those of healthy volunteers. We compared the resonance frequency (RF), maximum absorbance frequency (MAF), and maximum absorbance ratio (MAR). The t-test was used for statistical analysis with the significance level set to P<0.05. In addition, we used receiver operating characteristic analysis to derive cutoff values for SSCD diagnosis in terms of sensitivity and specificity.
Seventeen patients (four with bilateral and 13 with unilateral disease; 17 ears) diagnosed with SSCD and 27 healthy volunteers (47 ears) were included. The mean RFs of the SSCD patients and healthy subjects were 548.7 Hz (range, 243 to 853 Hz) and 935.1 Hz (range, 239 to 1,875 Hz), respectively (P<0.001). The mean MARs of the SSCD patients and healthy subjects were 89.4% (range, 62% to 100%) and 82.4% (range, 63% to 99%), respectively (P=0.005). The mean MAFs of the SSCD patients and healthy subjects were 1,706.3 Hz (range, 613 to 3,816 Hz) and 2,668 Hz (range, 876 to 4,387 Hz), respectively (P<0.001). In terms of SSCD diagnosis, a MAR above 86% afforded 81% sensitivity and 77% specificity; an RF below 728 Hz, 86% sensitivity and 81% specificity; and an MAF below 1,835 Hz, 79% sensitivity and 67% specificity.
WBT may be a useful clinical screening test for SSCD. The RF and MAF were lower, and the MAR higher, in SSCD patients than in normal controls.
我们探讨了宽带鼓室声导抗测试(WBT)是否可作为上半规管裂(SSCD)的筛查试验,并获取了SSCD患者的新WBT数据(鉴于该测试尚未在临床广泛应用)。
我们将2013年至2018年期间在我院临床及影像学诊断为SSCD的患者的WBT数据与健康志愿者的进行比较。比较了共振频率(RF)、最大吸收频率(MAF)和最大吸收率(MAR)。采用t检验进行统计分析,显著性水平设定为P<0.05。此外,我们使用受试者工作特征分析得出SSCD诊断的敏感性和特异性方面的截断值。
纳入了17例诊断为SSCD的患者(4例双侧病变,13例单侧病变;共17耳)和27名健康志愿者(47耳)。SSCD患者和健康受试者的平均RF分别为548.7Hz(范围243至853Hz)和935.1Hz(范围239至1875Hz)(P<0.001)。SSCD患者和健康受试者的平均MAR分别为89.4%(范围62%至100%)和82.4%(范围63%至99%)(P=0.005)。SSCD患者和健康受试者的平均MAF分别为1706.3Hz(范围613至3816Hz)和2668Hz(范围876至4387Hz)(P<0.001)。在SSCD诊断方面,MAR高于86%时,敏感性为81%,特异性为77%;RF低于728Hz时,敏感性为86%,特异性为81%;MAF低于1835Hz时,敏感性为79%,特异性为67%。
WBT可能是一种用于SSCD的有用临床筛查试验。与正常对照相比,SSCD患者的RF和MAF较低,而MAR较高。