Han Dong-Gyun, Lee Chang-Ju
Department of Neurology, DaeJeon HanKook Hospital, 496-15 SungNam 2 Dong, DaeJeon, ChungCheongNam-Do 300-709, South Korea.
Med Hypotheses. 2009 Oct;73(4):561-3. doi: 10.1016/j.mehy.2009.05.047. Epub 2009 Jun 27.
Referred pain from visceral organs tends to be expressed on the specific area of body surface, called as Head's zone. Although it is well known that sympathetic referred pains of viscera appear on the body trunk, the fact that parasympathetic referred pains exist and are expressed on the head, sacrum and posterior thigh is not appreciated properly. Functional gastrointestinal diseases accompany frequently headache, and cyclic vomiting and recurrent abdominal pains in childhood progress to migraine later. Such clinical observations on relationship between headache and viscera suggest that longstanding disease processes of viscera could induce central sensitization of trigeminocervical nuclear complex, and express "parasympathetic referred pain" on the head, like sympathetic referred pain on the body trunk, that is headache.
来自内脏器官的牵涉痛往往表现在身体表面的特定区域，称为海德带。虽然众所周知内脏的交感神经牵涉痛出现在躯干，但副交感神经牵涉痛存在并表现在头部、骶骨和大腿后部这一事实并未得到充分认识。功能性胃肠疾病常伴有头痛，儿童期的周期性呕吐和反复腹痛后来会发展为偏头痛。这些关于头痛与内脏关系的临床观察表明，内脏的长期疾病过程可诱导三叉颈神经核复合体的中枢敏化，并像躯干上的交感神经牵涉痛一样在头部表现出“副交感神经牵涉痛”，即头痛。
