Sincich Lawrence C, Zhang Yuhua, Tiruveedhula Pavan, Horton Jonathan C, Roorda Austin
Beckman Vision Center, University of California, San Francisco, San Francisco, California, USA.
Nat Neurosci. 2009 Aug;12(8):967-9. doi: 10.1038/nn.2352. Epub 2009 Jun 28.
With the current techniques available for mapping receptive fields, it is impossible to resolve the contribution of single cone photoreceptors to the response of central visual neurons. Using adaptive optics to correct for ocular aberrations, we delivered micron-scale spots of light to the receptive field centers of neurons in the macaque lateral geniculate nucleus. Parvocellular LGN neurons mapped in this manner responded with high reliability to stimulation of single cones.
利用现有的用于绘制感受野的技术，无法分辨单个视锥光感受器对中枢视觉神经元反应的贡献。我们使用自适应光学技术校正眼像差，将微米级光斑投射到猕猴外侧膝状核中神经元的感受野中心。以这种方式绘制的小细胞外侧膝状核神经元对单个视锥的刺激反应具有高度可靠性。
