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疑似外周血管疾病患者踝肱指数的示波测量:与多普勒法比较

Oscillometric measurement of ankle-brachial index in patients with suspected peripheral disease: comparison with Doppler method.

作者信息

Diehm N, Dick F, Czuprin C, Lawall H, Baumgartner I, Diehm C

机构信息

Swiss Cardiovascular Center, Division of Clinical and Interventional Angiology, University Hospital Insel, Bern, Switzerland.

出版信息

Swiss Med Wkly. 2009 Jun 27;139(25-26):357-63. doi: 10.4414/smw.2009.12636.

Abstract

QUESTION UNDER STUDY

Purpose was to validate accuracy and reliability of automated oscillometric ankle-brachial (ABI) measurement prospectively against the current gold standard of Doppler-assisted ABI determination.

METHODS

Oscillometric ABI was measured in 50 consecutive patients with peripheral arterial disease (n = 100 limbs, mean age 65 +/- 6 years, 31 men, 19 diabetics) after both high and low ABI had been determined conventionally by Doppler under standardised conditions. Correlation was assessed by linear regression and Pearson product moment correlation. Degree of inter-modality agreement was quantified by use of Bland and Altman method.

RESULTS

Oscillometry was performed significantly faster than Doppler-assisted ABI (3.9 +/- 1.3 vs 11.4 +/- 3.8 minutes, P <0.001). Mean readings were 0.62 +/- 0.25, 0.70 +/- 0.22 and 0.63 +/- 0.39 for low, high and oscillometric ABI, respectively. Correlation between oscillometry and Doppler ABI was good overall (r = 0.76 for both low and high ABI) and excellent in oligo-symptomatic, non-diabetic patients (r = 0.81; 0.07 +/- 0.23); it was, however, limited in diabetic patients and in patients with critical limb ischaemia. In general, oscillometric ABI readings were slightly higher (+0.06), but linear regression analysis showed that correlation was sustained over the whole range of measurements.

CONCLUSIONS

Results of automated oscillometric ABI determination correlated well with Doppler-assisted measurements and could be obtained in shorter time. Agreement was particularly high in oligo-symptomatic non-diabetic patients.

摘要

研究问题

目的是前瞻性地验证自动振荡式踝臂指数(ABI)测量相对于当前多普勒辅助ABI测定金标准的准确性和可靠性。

方法

在50例连续的外周动脉疾病患者(n = 100条肢体,平均年龄65±6岁,31名男性,19名糖尿病患者)中,在标准化条件下通过多普勒常规测定高低ABI后,测量振荡式ABI。通过线性回归和Pearson积矩相关评估相关性。使用Bland和Altman方法量化模态间一致性程度。

结果

振荡测量比多普勒辅助ABI测量明显更快(3.9±1.3分钟对11.4±3.8分钟,P<0.001)。低、高和振荡式ABI的平均读数分别为0.62±0.25、0.70±0.22和0.63±0.39。振荡测量与多普勒ABI之间的总体相关性良好(低和高ABI的r均为0.76),在症状轻微的非糖尿病患者中相关性极佳(r = 0.81;0.07±0.23);然而,在糖尿病患者和严重肢体缺血患者中相关性有限。一般来说,振荡式ABI读数略高(+0.06),但线性回归分析表明,在整个测量范围内相关性持续存在。

结论

自动振荡式ABI测定结果与多普勒辅助测量相关性良好,且可在更短时间内获得。在症状轻微的非糖尿病患者中一致性尤其高。

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