危重症中毒患者的处理。
Management of the critically poisoned patient.
机构信息
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
出版信息
Scand J Trauma Resusc Emerg Med. 2009 Jun 29;17:29. doi: 10.1186/1757-7241-17-29.
BACKGROUND
Clinicians are often challenged to manage critically ill poison patients. The clinical effects encountered in poisoned patients are dependent on numerous variables, such as the dose, the length of exposure time, and the pre-existing health of the patient. The goal of this article is to introduce the basic concepts for evaluation of poisoned patients and review the appropriate management of such patients based on the currently available literature.
METHODS
An unsystematic review of the medical literature was performed and articles pertaining to human poisoning were obtained. The literature selected was based on the preference and clinical expertise of authors.
DISCUSSION
If a poisoning is recognized early and appropriate testing and supportive care is initiated rapidly, the majority of patient outcomes will be good. Judicious use of antidotes should be practiced and clinicians should clearly understand the indications and contraindications of antidotes prior to administration.
背景
临床医生在治疗重症中毒患者时经常面临挑战。中毒患者的临床效果取决于许多变量，例如剂量、暴露时间的长短以及患者的原有健康状况。本文的目的是介绍评估中毒患者的基本概念，并根据现有文献复习此类患者的适当处理方法。
方法
对医学文献进行非系统性回顾，并获取有关人类中毒的文章。选择的文献基于作者的偏好和临床专业知识。
讨论
如果早期识别中毒并迅速开始适当的检测和支持性治疗，大多数患者的预后将良好。解毒剂的合理使用应加以实践，临床医生在使用解毒剂之前应清楚了解其适应证和禁忌证。
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