Mitler M M, Lund R, Sokolove P G, Pittendrigh C S, Dement W C
Brain Res. 1977 Aug 5;131(1):129-45. doi: 10.1016/0006-8993(77)90033-6.
Studies on daily and circadian rhythms in wheel running and electrographically defined wakefulness, NREM sleep, and REM sleep in M. musculus were done to gather data on the temporal distribution of activity and sleep. Generally, peaks in NREM and sleep tended to coincide and to alternate with the coincident peaks of wakefulness and wheel running. However, during the active phase of the circadian wheel running cycle some NREM and REM sleep did occur; conversely, during its rest phase, wakefulness was often present. The most striking finding was that in mice with clearly entrained or free-running activity onsets, the circadian peak-through patterns in wakefulness, NREM, and REM sleep were not always distinct--they could be damped and/or polyphasic. Several explanations of these phenomena are considered.
对小家鼠的转轮活动以及通过脑电图定义的清醒、非快速眼动睡眠和快速眼动睡眠的日节律和昼夜节律进行了研究，以收集有关活动和睡眠的时间分布数据。一般来说，非快速眼动睡眠和睡眠的峰值往往重合，并与清醒和转轮活动的重合峰值交替出现。然而，在昼夜转轮活动周期的活跃阶段，确实会出现一些非快速眼动睡眠和快速眼动睡眠；相反，在其休息阶段，清醒状态也经常出现。最引人注目的发现是，在活动起始明显受生物钟调节或自由运行的小鼠中，清醒、非快速眼动睡眠和快速眼动睡眠的昼夜峰值-谷值模式并不总是清晰的——它们可能会减弱和/或呈多相性。本文考虑了对这些现象的几种解释。
