Andreux J P, Renard M, Daffos F, Forestier F
Laboratoire d'Hématologie, Hôpital J. Rostand, Ivry, France.
Nouv Rev Fr Hematol (1978). 1991;33(3):223-6.
Ultrasound guided fetal blood sampling performed for diagnostic purposes allowed us to determine the circulating level of erythropoietic progenitor cells (BFU-E) from the 19th to 30th weeks of gestation. Normal fetal blood showed a mean of 160 BFU-E (+/- 107) per 10(5) nucleated cells during the second and third trimesters of pregnancy, which is 3 times higher than in cord blood at birth and 10 times higher than in adult bone marrow. These findings are in keeping with an important circulation of hematopoietic progenitors during fetal life.
为诊断目的进行的超声引导下胎儿采血使我们能够测定妊娠第19至30周期间促红细胞生成祖细胞（BFU-E）的循环水平。正常胎儿血液在妊娠中期和晚期每10⁵有核细胞中平均有160个BFU-E（±107），这比出生时脐带血中的水平高3倍，比成人骨髓中的水平高10倍。这些发现与胎儿期造血祖细胞的重要循环情况相符。
