Costa Elisa, Tormo Nuria, Clari María Angeles, Bravo Dayana, Muñoz-Cobo Beatriz, Navarro David
Service of Microbiology, Hospital Clínico Universitario, Valencia, Spain.
Clin Vaccine Immunol. 2009 Aug;16(8):1247-8. doi: 10.1128/CVI.00142-09. Epub 2009 Jul 1.
Acute parvovirus B19 infection has been reported to cause false-positive results frequently in the Epstein-Barr (EBV) and herpes simplex virus (HSV) immunoglobulin M (IgM) assays from DiaSorin performed on the Liaison platform. We tested 65 sera from patients with a presumptive or conclusive diagnosis of acute parvovirus B19 infection in both assays and obtained no false-positive results in the EBV IgM test and 10.4% nonspecific reactivities in the HSV IgM assay. Our data support the specificity of both assays in this clinical setting.
据报道,在Liaison平台上使用DiaSorin公司的检测方法检测爱泼斯坦-巴尔病毒(EBV)和单纯疱疹病毒(HSV)免疫球蛋白M(IgM)时,急性细小病毒B19感染常导致假阳性结果。我们对65份来自临床诊断为急性细小病毒B19感染的患者血清进行了这两种检测,EBV IgM检测未获得假阳性结果,HSV IgM检测出现了10.4%的非特异性反应。我们的数据支持了这两种检测方法在该临床环境中的特异性。