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Transporters for drug delivery and as drug targets in parasitic protozoa.
Clin Pharmacol Ther. 2010 Jan;87(1):122-5. doi: 10.1038/clpt.2009.116. Epub 2009 Jul 1.
2
Delivery strategies for antiparasitics.
Expert Opin Investig Drugs. 2003 Feb;12(2):197-207. doi: 10.1517/13543784.12.2.197.
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Role of Polyamines in Parasite Cell Architecture and Function.
Curr Pharm Des. 2017;23(23):3342-3358. doi: 10.2174/1381612823666170703163458.
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Mitochondria as a promising antiparasitic target.
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Heme metabolism as a therapeutic target against protozoan parasites.
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Protein kinases as targets for antiparasitic chemotherapy drugs.
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Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs.
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Diversity, expression, and structural modeling of sugar transporters in s. s. L3 and L4 larvae: an and study.
Front Cell Infect Microbiol. 2025 Aug 20;15:1621051. doi: 10.3389/fcimb.2025.1621051. eCollection 2025.
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TryTransDB: A web-based resource for transport proteins in Trypanosomatidae.
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Quinone-amino acid conjugates targeting Leishmania amino acid transporters.
PLoS One. 2014 Sep 25;9(9):e107994. doi: 10.1371/journal.pone.0107994. eCollection 2014.
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The effect of tunicamycin on the glucose uptake, growth, and cellular adhesion in the protozoan parasite Crithidia fasciculata.
Curr Microbiol. 2014 Oct;69(4):541-8. doi: 10.1007/s00284-014-0620-x. Epub 2014 Jun 4.

本文引用的文献

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An acid-activated nucleobase transporter from Leishmania major.
J Biol Chem. 2009 Jun 12;284(24):16164-16169. doi: 10.1074/jbc.M109.006718. Epub 2009 Apr 14.
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Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.
Bioorg Med Chem. 2009 Mar 15;17(6):2512-23. doi: 10.1016/j.bmc.2009.01.058. Epub 2009 Jan 31.
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Two novel nucleobase/pentamidine transporters from Trypanosoma brucei.
Mol Biochem Parasitol. 2009 Feb;163(2):67-76. doi: 10.1016/j.molbiopara.2008.09.011. Epub 2008 Oct 17.
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Purine and pyrimidine metabolism in Leishmania.
Adv Exp Med Biol. 2008;625:141-54. doi: 10.1007/978-0-387-77570-8_12.
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Molecular genetic analysis of purine nucleobase transport in Leishmania major.
Mol Microbiol. 2007 Jun;64(5):1228-43. doi: 10.1111/j.1365-2958.2007.05730.x.
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Targeting of toxic compounds to the trypanosome's interior.
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ABC transporters in Leishmania and their role in drug resistance.
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A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.
J Exp Med. 2006 Oct 2;203(10):2363-75. doi: 10.1084/jem.20060559. Epub 2006 Sep 25.
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Purine nucleobase transport in amastigotes of Leishmania mexicana: involvement in allopurinol uptake.
Antimicrob Agents Chemother. 2005 Sep;49(9):3682-9. doi: 10.1128/AAC.49.9.3682-3689.2005.

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