Golan Abraham, Weissman Ariel
IVF Unit, Department of Obstetrics and Gynecology, Wolfson Medical Center, Holon 58100, Israel.
Reprod Biomed Online. 2009 Jul;19(1):28-32. doi: 10.1016/s1472-6483(10)60042-9.
Ovarian hyperstimulation syndrome (OHSS) is a serious iatrogenic complication of ovarian stimulation using fertility medications. OHSS classification presents the different severity categories and grades of OHSS and optimizes management schemes and prognosis. An initial classification system, which grouped OHSS into mild, moderate and severe categories, was based on patients' symptomatology plus manual estimation of ovarian enlargement and urinary excretion of sex steroids. A revised classification system then also incorporated the use of transvaginal sonography for both estimation of ovarian enlargement and detection of even small amounts of ascitic fluid. The detection of ascites establishes the diagnosis of moderate OHSS which may deteriorate to a severe form and is therefore of major importance. Subsequent modifications defined a group of critical or complicated OHSS in which grave complications have already developed. A consensus on the classification of OHSS should be reached by professional societies. As the revised classification system is very valid and widely used, it should form the basis for a modern classification, with the addition of critical or complicated OHSS to the severe category of the syndrome.
卵巢过度刺激综合征（OHSS）是使用促生育药物进行卵巢刺激引发的一种严重医源性并发症。OHSS分类呈现了OHSS的不同严重程度类别和等级，并优化了管理方案和预后。最初的分类系统是根据患者的症状加上对卵巢增大情况的手动估计以及性类固醇的尿排泄量，将OHSS分为轻度、中度和重度类别。随后修订的分类系统还纳入了经阴道超声检查，用于估计卵巢增大情况以及检测哪怕少量的腹水。腹水的检测确立了中度OHSS的诊断，而中度OHSS可能恶化为重度形式，因此至关重要。后续的修订定义了一组危急或复杂的OHSS，其中已经出现了严重并发症。专业协会应就OHSS的分类达成共识。由于修订后的分类系统非常有效且被广泛使用，它应成为现代分类的基础，在该综合征的重度类别中增加危急或复杂的OHSS。
