Wang C C, Tsou C L
Division of Biochemistry and Biophysics, Food and Drug Administration, Bethesda, MD 20892.
Trends Biochem Sci. 1991 Aug;16(8):279-81. doi: 10.1016/0968-0004(91)90114-b.
Refolding studies show that native insulin can be reformed from A and B chains only. This suggests that the A and B chains contain the necessary structural information and that the C peptide is not required for this process.
复性研究表明,天然胰岛素仅可由A链和B链重新形成。这表明A链和B链包含必要的结构信息,且该过程不需要C肽。