Wenner Joshua B, Norena Monica, Khan Nadia, Palepu Anita, Ayas Najib T, Wong Hubert, Dodek Peter M
Center for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, BC Canada.
J Crit Care. 2009 Sep;24(3):401-7. doi: 10.1016/j.jcrc.2009.03.008. Epub 2009 Jul 3.
Although reliability of severity of illness and predicted probability of hospital mortality have been assessed, interrater reliability of the abstraction of primary and other intensive care unit (ICU) admitting diagnoses and underlying comorbidities has not been studied.
Patient data from one ICU were originally abstracted and entered into an electronic database by an ICU nurse. A research assistant reabstracted patient demographics, ICU admitting diagnoses and underlying comorbidities, and elements of Acute Physiology and Chronic Health Evaluation II (APACHE II) score from 100 random patients of 474 admitted during 2005 using an identical electronic database. Chamberlain's percent positive agreement was used to compare diagnoses and comorbidities between the 2 data abstractors. A kappa statistic was calculated for demographic variables, Glasgow Coma Score, APACHE II chronic health points, and HIV status. Intraclass correlation was calculated for acute physiology points and predicted probability of hospital mortality.
Percent positive agreement for ICU primary and other admitting diagnoses ranged from 0% (primary brain injury) to 71% (sepsis), and for underlying comorbidities, from 40% (coronary artery bypass graft) to 100% (HIV). Agreement as measured by kappa statistic was strong for race (0.81) and age points (0.95), moderate for chronic health points (0.50) and HIV (0.66), and poor for Glasgow Coma Score (0.36). Intraclass correlation showed a moderate-high agreement for acute physiology points (0.88) and predicted probability of hospital mortality (0.71).
Reliability for ICU diagnoses and elements of the APACHE II score is related to the objectivity of primary data in the medical charts.
尽管已经评估了疾病严重程度和医院死亡率预测概率的可靠性,但对于重症监护病房(ICU)主要及其他入院诊断和潜在合并症提取的评分者间可靠性尚未进行研究。
一名ICU护士最初提取了一个ICU的患者数据并录入电子数据库。一名研究助理使用相同的电子数据库,从2005年收治的474例患者中随机抽取100例,重新提取患者人口统计学资料、ICU入院诊断和潜在合并症,以及急性生理与慢性健康状况评价Ⅱ(APACHEⅡ)评分的各项内容。采用张伯伦阳性一致率比较两位数据提取者之间的诊断和合并症情况。计算人口统计学变量、格拉斯哥昏迷评分、APACHEⅡ慢性健康评分及HIV状态的kappa统计量。计算急性生理评分和医院死亡率预测概率的组内相关系数。
ICU主要及其他入院诊断的阳性一致率范围为0%(原发性脑损伤)至71%(脓毒症),潜在合并症的阳性一致率范围为40%(冠状动脉搭桥术)至100%(HIV)。kappa统计量显示种族(0.81)和年龄评分(0.95)的一致性较强,慢性健康评分(0.50)和HIV(0.66)的一致性中等,格拉斯哥昏迷评分(0.36)的一致性较差。组内相关系数显示急性生理评分(0.88)和医院死亡率预测概率(0.71)的一致性为中高度。
ICU诊断及APACHEⅡ评分各项内容的可靠性与病历中原始数据的客观性相关。