Roscić Vesna, Bojić Lovro, Marović Terezija
Ustanova za hitnu medicinsku pomoć Split, Hrvatska.
Acta Med Croatica. 2009 May;63(2):169-72.
The aim of this study was to determine the incidence of nonarteritic ischemic optic neuropathy (NAION) in the Split-Dalmatia County, Croatia, as part of the Mediterranean region of southern Europe, during a 7-year period (2001-2007). This retrospective study included 87 NAION patients (36 female, median age 68 years, and 51 male, median age 69.5 years) treated at University Department of Ophthalmology, Split University Hospital Center, from January 2001 till December 2007. In each case the diagnosis was confirmed by review of patient records. The annual incidence of NAION was 2.9 per 100,000 (95% CI 1.1-4.8); 3.8 (95% Cl 0.76-6.8) per 100,000 per year in male and 2.5 (95% CI 0.12-4.9) per 100,000 per year in female patients. There was no statistically significant sex difference in the annual incidence of NAION (chi2 = 1.17; P = 0.279). NAION involvement showed a statistically significant male predominance in the > 65 year age group, yielding a relative risk for men vs. women of 1.75. In conclusion, the incidence of NAION in the Split-Dalmatia County was found to be moderate.
本研究的目的是确定在7年期间（2001 - 2007年），克罗地亚斯普利特 - 达尔马提亚县（作为南欧地中海地区的一部分）非动脉炎性缺血性视神经病变（NAION）的发病率。这项回顾性研究纳入了2001年1月至2007年12月期间在斯普利特大学医院中心眼科大学部接受治疗的87例NAION患者（36例女性，中位年龄68岁；51例男性，中位年龄69.5岁）。每例患者的诊断均通过查阅病历记录得以确认。NAION的年发病率为每10万人2.9例（95%可信区间1.1 - 4.8）；男性患者每年每10万人3.8例（95%可信区间0.76 - 6.8），女性患者每年每10万人2.5例（95%可信区间0.12 - 4.9）。NAION的年发病率在性别上无统计学显著差异（卡方 = 1.17；P = 0.279）。在65岁以上年龄组中，NAION受累情况显示男性占主导地位，男性与女性的相对风险为1.75。总之，发现斯普利特 - 达尔马提亚县NAION的发病率为中等水平。
