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循证医学与考克兰协作网

Evidence-based medicine and the Cochrane Collaboration.

作者信息

Tanjong-Ghogomu Elizabeth, Tugwell Peter, Welch Vivian

机构信息

University of Ottawa, Ottawa, Canada.

出版信息

Bull NYU Hosp Jt Dis. 2009;67(2):198-205.

PMID:19583554
Abstract

Providing evidence-based care to patients involves turning a clinical problem into an answerable question, systematically searching for the best evidence relevant to the question, critically appraising that evidence, and, finally, using the evidence as the basis for clinical decisions to solve the problem. While the overload of medical information today presents a demanding challenge to physicians to sort and identify relevant and valid evidence, it is vitally important to translate that evidence into clinically useful terms. To apply evidence to patient clinical management, it is critical to discuss with patients the evidence, the benefits and the harms, and the alternative treatments, such that they understand and can fully participate in the decision-making process. The framework of evidenced-based medicine provides a concrete methodology to address these issues, here, framed and detailed in five steps. The Cochrane Collaboration has been at the forefront of applying the methods of evidence-based medicine (EBM) in the treatment and management of musculoskeletal and other disorders.

摘要

为患者提供循证护理包括将临床问题转化为可回答的问题,系统地寻找与该问题相关的最佳证据,严格评估该证据,最后,将证据作为临床决策的基础来解决问题。尽管如今医学信息过载给医生筛选和识别相关且有效的证据带来了严峻挑战,但将这些证据转化为临床可用的术语至关重要。为了将证据应用于患者的临床管理,与患者讨论证据、益处和危害以及替代治疗方法非常关键,这样他们才能理解并充分参与决策过程。循证医学框架提供了一种具体方法来解决这些问题,在此以五个步骤进行阐述和详细说明。Cochrane协作网在将循证医学(EBM)方法应用于肌肉骨骼及其他疾病的治疗和管理方面一直处于前沿。

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Evidence-based medicine and the Cochrane Collaboration.循证医学与考克兰协作网
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Outcomes in Clinical Trials Evaluating Interventions for the Prevention and Treatment of Hepatic Encephalopathy.
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Assessments of attrition bias in Cochrane systematic reviews are highly inconsistent and thus hindering trial comparability.对 Cochrane 系统评价中损耗偏倚的评估高度不一致,从而阻碍了试验之间的可比性。
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