Sgorbini Myra, O'Brien Louise, Jackson Debra
Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia.
J Clin Nurs. 2009 Aug;18(16):2282-91. doi: 10.1111/j.1365-2702.2009.02806.x.
The purpose of the study was to explore the issues surrounding chronic hepatitis C, combination therapy and its impact on personal relationships to enhance understanding of the experiences of patients living with hepatitis C. This paper focuses on the experiences of the patients and their partners' experiences will be published separately.
Patients with chronic hepatitis C who have active inflammatory changes on liver biopsy may undergo combination therapy with interferon and ribavirin. For some patients, the adverse effects of combination therapy are so severe that it can potentially place an enormous stress on personal relationships.
The study was informed by Heideggerian phenomenology.
Purposive sampling and semi-structured interviews of five patients and their partners were conducted between 2004-2006 in Sydney Australia, to obtain a rich description of their experiences.
The findings from this study revealed that chronic hepatitis C and combination therapy had an enormous impact on the lives of the patients, their partners and families. The illness and treatment had significant physiological effects that had an impact on quality of life; however, the social and psychological consequences of living with a highly stigmatised disease with an unknown course and outcome cannot be underestimated.
The results of this study lend support to the effectiveness of providing equitable services to persons diagnosed with chronic hepatitis C. However, additional research is needed to explore gender, socioeconomic, sexual-orientation, transmission, cultural, religious and genotype differences in this group to address their needs better.
Nurses play a significant role in educating patients with chronic hepatitis C, advocating for them and helping them to achieve a reasonable state of well being. Through deeper understanding of their experiences of illness and treatment, nurses can move beyond the medical oriented approach to care.
本研究旨在探讨围绕慢性丙型肝炎、联合治疗及其对人际关系的影响等问题,以增进对丙型肝炎患者经历的理解。本文聚焦于患者的经历,其伴侣的经历将另行发表。
肝活检显示有活动性炎症变化的慢性丙型肝炎患者可能会接受干扰素和利巴韦林的联合治疗。对一些患者来说,联合治疗的不良反应非常严重,可能会给人际关系带来巨大压力。
本研究以海德格尔现象学为指导。
2004年至2006年期间,在澳大利亚悉尼对五名患者及其伴侣进行了目的抽样和半结构化访谈,以丰富描述他们的经历。
本研究结果显示,慢性丙型肝炎和联合治疗对患者及其伴侣和家庭的生活产生了巨大影响。疾病和治疗产生了显著的生理影响,进而影响生活质量;然而,患有一种高度污名化、病程和结局不明的疾病所带来的社会和心理后果不可低估。
本研究结果支持为被诊断为慢性丙型肝炎的患者提供公平服务的有效性。然而,需要进一步研究以探讨该群体在性别、社会经济、性取向、传播途径、文化、宗教和基因型方面的差异,以便更好地满足他们的需求。
护士在教育慢性丙型肝炎患者、为他们提供支持并帮助他们达到合理的健康状态方面发挥着重要作用。通过更深入地了解他们的疾病和治疗经历,护士可以超越以医疗为导向的护理方法。