Mittal Pardeep, S Matreja Prithpal, Rao H K, Khanna Pml
Gian Sagar Medical College and Hospital, Patiala, Punjab, India.
Department of Pharmacology, Gian Sagar Medical College and Hospital, Patiala, Punjab, India.
Euroasian J Hepatogastroenterol. 2015 Jul-Dec;5(2):90-94. doi: 10.5005/jp-journals-10018-1142. Epub 2016 Jul 9.
Hepatitis is a disorder which is emerging as major health problem with increasing morbidity and mortality. Inappropriate management of this disease leads to several complications that can impair the health related quality of life (HRQoL) of the individuals. There, we designed this study to assess the HRQoL in patients suffering from hepatitis.
This prospective, observational study was conducted for 2 months in patients with hepatitis. All patients with hepatitis were recruited in the study after giving written informed consent. The participants were given both World Health Organization Quality of Life-Bref (WHO QoL-Bref) and short form (SF-36) health survey questionnaires for assessing the quality of life (QoL) of patients. The participants were given counseling of lifestyle modification and underwent a thorough medical examination and a detailed history was taken.
A total of 65 volunteers participated in the study, out of which 30 were control and 35 were patients suffering from hepatitis; hepatitis C was found to be more prevalent. The patients with hepatitis had a significantly poor QoL as compared to control. In hepatitis patients, physical health and physical functioning was better in males as compared to females. Social relationships were also good in males than females. But females had higher score in role limitation due to physical health, emotional wellbeing, social functioning, pain, general health as per SF-36 scores but it was not statistically significant.
Hepatitis affected the HRQoL in Indian population and parameters seem to be heterogeneously affected in males and females.
Mittal P, Matreja PS, Rao HK, Khanna PML. Prevalence and Impact of Hepatitis on the Quality of Life of Patients. Euroasian J Hepato-Gastroenterol 2015;5(2):90-94.
肝炎是一种发病率和死亡率不断上升的疾病,正逐渐成为主要的健康问题。对该疾病的不当管理会导致多种并发症,进而损害个体的健康相关生活质量(HRQoL)。因此,我们设计了本研究来评估肝炎患者的HRQoL。
本前瞻性观察性研究对肝炎患者进行了为期2个月的观察。所有肝炎患者在签署书面知情同意书后纳入研究。参与者均接受了世界卫生组织生活质量简表(WHO QoL - Bref)和简短健康调查问卷(SF - 36),以评估患者的生活质量(QoL)。参与者接受了生活方式改变的咨询,并接受了全面的体格检查和详细的病史采集。
共有65名志愿者参与了本研究,其中30名作为对照组,35名是肝炎患者;发现丙型肝炎更为普遍。与对照组相比,肝炎患者的QoL明显较差。在肝炎患者中,男性的身体健康和身体功能状况优于女性。男性的社会关系也比女性好。但根据SF - 36评分,女性在因身体健康导致的角色限制、情绪健康、社会功能、疼痛、总体健康方面得分较高,但差异无统计学意义。
肝炎影响了印度人群的HRQoL,且男性和女性的各项参数似乎受到了不同程度的影响。
Mittal P, Matreja PS, Rao HK, Khanna PML. 肝炎对患者生活质量的患病率及影响。《欧亚肝脏胃肠病学杂志》2015年;5(2):90 - 94。