The University Clinical Center Tuzla, Trnovac bb, Tuzla, Bosnia and Herzegovina.
J Hypertens. 2009 Oct;27(10):2074-8. doi: 10.1097/HJH.0b013e32832f1458.
To evaluate the relationships between simple renal cysts and arterial hypertension and whether their evacuation decreases the blood pressure (BP).
In a cross-sectional design, we analyzed 184 study participants with cysts and compared hypertensive and nonhypertensive among them. Outcomes were the number, the size and the location of a cyst. In a cross-over design, we first evaluated the change in absolute value of SBP, DBP and mean BP in 62 hypertensive patients who underwent percutaneous evacuation of a cyst and then the decrease of BP as a categorical variable that comprised all study participants.
There were 55% giant renal cysts among hypertensive and 24% among nonhypertensive patients (P = 0.0001). The prevalence rates of multiple and peripheral cysts in hypertensive and nonhypertensive patients were similar to those of single and perihilar cysts, respectively. Significant differences in SBP, DBP and mean BP were found between pretreatment readings and 3 days, 1 month, 3 months and 6 months after cyst evacuation (P < 0001). The differences were significant in all hypertensive patients (P < 0.001). There were less hypertensive patients 3 days after treatment than before treatment (P < 0.0001).
An apparent association between the size of a simple renal cyst and hypertension was found, and aspiration of cysts resulted in a reduction of BP. Location and number of cysts were not related to BP.
评估单纯性肾囊肿与动脉高血压之间的关系，以及囊肿排空是否会降低血压（BP）。
在一项横断面设计中，我们分析了 184 名患有囊肿的研究参与者，并比较了其中的高血压和非高血压患者。结果包括囊肿的数量、大小和位置。在一项交叉设计中，我们首先评估了 62 名高血压患者在进行囊肿经皮排空后 SBP、DBP 和平均 BP 的绝对值变化，然后将 BP 作为一个分类变量进行评估，该变量包含了所有研究参与者。
高血压患者中有 55%的囊肿为巨大肾囊肿，而非高血压患者中只有 24%（P = 0.0001）。高血压和非高血压患者中多发性和外周性囊肿的患病率与单发性和周边性囊肿的患病率相似。在囊肿排空前和 3 天、1 个月、3 个月和 6 个月后，SBP、DBP 和平均 BP 的治疗前读数之间存在显著差异（P < 0001）。所有高血压患者的差异均有统计学意义（P < 0.001）。治疗后 3 天的高血压患者少于治疗前（P < 0.0001）。
发现单纯性肾囊肿的大小与高血压之间存在明显的关联，囊肿抽吸可降低血压。囊肿的位置和数量与血压无关。
