Thomas Gethin, Whalley Helen, Modi Chetan
Foot Ankle Int. 2009 Jul;30(7):666-74. doi: 10.3113/FAI.2009.0666.
It is commonly believed that early motion after joint fixation is advantageous, especially in the upper limb. In the ankle joint this is much less clear. No previous systematic review of the evidence for this could be found in the literature.
Nine randomized control trials were identified which met the inclusion criteria and compared early motion of the ankle joint to immobilization in a cast for 6 weeks. These varied in quality and numbers. All treated patients equally in all other respects including weight bearing. Where outcome measures were similar, some data pooling was possible.
There is good evidence that early motion is associated with a quicker return to work on average (p = 0.008) and also with an improved range of motion at 12 weeks (dorsiflexion p = 0.001; plantarflexion p < 0.00001) compared to cast immobilization. However it is also associated with an increased risk of wound infection (p = 0.002). There is a suggestion that early motion results in a lower rate of deep vein thrombosis (p = 0.12). There is no evidence that it results in improved joint specific outcome scores or range of motion at 1 year.
It is difficult to conclude whether early motion is overall better or worse than cast immobilization. The evidence suggests however that a young fit patient who needs to return to work may benefit from early motion of the ankle joint whereas a patient with poor skin or at risk of infection may be better treated in a cast after surgery.
人们普遍认为关节固定术后早期活动是有益的,尤其是在上肢。在踝关节,情况则不太明确。此前在文献中未发现对此证据的系统综述。
确定了9项符合纳入标准的随机对照试验,这些试验将踝关节的早期活动与石膏固定6周进行了比较。这些试验在质量和数量上各不相同。所有患者在包括负重在内的所有其他方面均接受相同治疗。当结局指标相似时,可以进行一些数据合并。
有充分证据表明,与石膏固定相比,早期活动平均与更快恢复工作相关(p = 0.008),并且在12周时关节活动范围也有所改善(背屈p = 0.001;跖屈p < 0.00001)。然而,它也与伤口感染风险增加相关(p = 0.002)。有迹象表明早期活动会导致深静脉血栓形成率降低(p = 0.12)。没有证据表明它会导致1年后关节特定结局评分或活动范围得到改善。
很难得出早期活动总体上比石膏固定更好还是更差的结论。然而,证据表明,需要恢复工作的年轻健康患者可能会从踝关节早期活动中受益,而皮肤状况差或有感染风险的患者术后可能用石膏固定治疗更好。