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美国心脏病学会/美国心脏协会连续心电图解读指南对非心脏大手术后无症状性心肌缺血与肌钙蛋白释放之间关联的影响。

Impact of the American College of Cardiology/American Heart Association guidelines for interpretability of continuous electrocardiography on the association of silent ischemia with troponin release after major noncardiac surgery.

作者信息

Lurati Buse Giovanna A, Seeberger Manfred D, Schumann Regina M, Bürgler David, Schwab Hildebrand S, Bolliger Daniel, Filipovic Miodrag

机构信息

Department of Anesthesia, University of Basel, CH-4031 Basel, Switzerland.

出版信息

J Electrocardiol. 2009 Sep-Oct;42(5):455-461.e1. doi: 10.1016/j.jelectrocard.2009.05.008.

Abstract

INTRODUCTION

Preexisting electrocardiographic abnormalities may limit accuracy of continuous electrocardiography (cECG) for ischemia determination. The American College of Cardiology/American Heart Association published criteria for the exclusion of unsuitable cECG curves from ST-segment interpretation. These criteria consider medication and 12-lead ECG findings (medication- and 12-lead ECG-based criteria) and cECG lead characteristics (cECG-based criteria).

METHODS

We recorded cECG in 300 patients undergoing major noncardiac surgery. We determined postoperative troponin and 12-month outcome. We compared the associations of cECG-detected ischemia with troponin and 12-month outcome with and without adherence to the criteria.

RESULTS

Adherence to the medication- and 12-lead ECG-based criteria enhanced the association between troponin and perioperative ischemia in CM5 (odds ratio, 3.74; 95% confidence interval, 1.88-7.44) and 7.03 (2.67-18.49), respectively; P = .049). Similarly, the association between ischemia in CM5 and 12-month outcome tended to increase (P = .081).

CONCLUSIONS

Applying the guideline criteria for the interpretation of cECG enhanced cECG diagnostic value in surgical patients.

摘要

引言

既往心电图异常可能会限制连续心电图(cECG)用于确定缺血的准确性。美国心脏病学会/美国心脏协会发布了从ST段解读中排除不合适cECG曲线的标准。这些标准考虑了用药情况和12导联心电图结果(基于用药和12导联心电图的标准)以及cECG导联特征(基于cECG的标准)。

方法

我们记录了300例接受非心脏大手术患者的cECG。我们测定了术后肌钙蛋白和12个月的预后情况。我们比较了遵循和未遵循这些标准时,cECG检测到的缺血与肌钙蛋白以及12个月预后之间的关联。

结果

遵循基于用药和12导联心电图的标准分别增强了CM5导联中肌钙蛋白与围手术期缺血之间的关联(比值比,3.74;95%置信区间,1.88 - 7.44)以及7.03(2.67 - 18.49);P = 0.049)。同样,CM5导联缺血与12个月预后之间的关联也有增加趋势(P = 0.081)。

结论

应用cECG解读的指南标准可提高cECG在手术患者中的诊断价值。

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