Simon Carl G, Yang Yanyin, Thomas Vinoy, Dorsey Shauna M, Morgan Abby W
Polymers Division, National Institute of Standards & Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA.
Comb Chem High Throughput Screen. 2009 Jul;12(6):544-53. doi: 10.2174/138620709788681961.
Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.
梯度和阵列在组织工程和生物材料领域已变得非常有用。梯度和阵列都为筛选细胞对生物材料的反应提供了高效的平台。梯度生物材料也具有功能应用，并且为细胞迁移等细胞现象的基础研究提供了有用的基质。本文将综述梯度和阵列在组织工程和生物材料研究中的应用，重点关注细胞和生物学反应。
