Jang Ki Po, Kim Chan Hyuk, Na Seong Wook, Kim Hiyoung, Kang Heonjoong, Lee Eun
Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Republic of Korea.
Bioorg Med Chem Lett. 2009 Aug 15;19(16):4601-2. doi: 10.1016/j.bmcl.2009.06.092. Epub 2009 Jun 27.
Isoplatensimycin, a novel analog of platensimycin, was synthesized via intramolecular dipolar cycloaddition of a carbonyl ylide. Isoplatensimycin showed little activities against strains of Staphylococcus aureus, but exhibited activities against some vancomycin-resistant enteroccoci.
异普拉特烯霉素是普拉特烯霉素的一种新型类似物，通过羰基叶立德的分子内偶极环加成反应合成。异普拉特烯霉素对金黄色葡萄球菌菌株几乎没有活性，但对一些耐万古霉素肠球菌具有活性。
