Critchley M, Herman K J, Harrison M, Shields R A, Liversedge L A
J Neurol Neurosurg Psychiatry. 1977 Mar;40(3):250-2. doi: 10.1136/jnnp.40.3.250.
We have investigated electrolyte exchange in myasthenia gravis before and after corticotrophin therapy, using a four-isotope dilution technique. Clinical deterioration in patients on corticotrophin is associated with a fall of more than 20% in the intracellular potassium concentration, suggesting that all myasthenics so treated should be given potassium supplementation.
我们采用四同位素稀释技术,研究了促肾上腺皮质激素治疗前后重症肌无力患者的电解质交换情况。接受促肾上腺皮质激素治疗的患者临床病情恶化与细胞内钾浓度下降超过20%有关,这表明所有接受该治疗的重症肌无力患者都应补充钾。