重症肌无力患者使用促肾上腺皮质激素的获益。
Benefit from adrenocorticotrophin in myasthenia gravis.
作者信息
Liversedge L A, Yuill G M, Wilkinson I M, Hughes J A
出版信息
J Neurol Neurosurg Psychiatry. 1974 Apr;37(4):412-5. doi: 10.1136/jnnp.37.4.412.
Abstract
Twenty-one of 29 patients suffering from myasthenia gravis derived benefit from a short intensive course of adrenocorticotrophin (ACTH). The mean duration of benefit was approximately six months. The best results were obtained in patients with a short history of myasthenia. Transient deterioration during the course of injections was encountered in some cases but necessitated assisted respiration only in patients with severe generalized weakness before treatment.
摘要
29例重症肌无力患者中有21例从短期强化促肾上腺皮质激素（ACTH）治疗中获益。获益的平均持续时间约为6个月。重症肌无力病史较短的患者取得了最佳疗效。部分病例在注射过程中出现短暂病情恶化，但仅在治疗前有严重全身无力的患者中需要辅助呼吸。
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3
The place of corticotropin in the treatment of myasthenia gravis.促肾上腺皮质激素在重症肌无力治疗中的地位。
Ann Intern Med. 1960 Apr;52:806-18. doi: 10.7326/0003-4819-52-4-806.
4
Corticosteroids in management of severe, generalized myasthenia gravis. Effectiveness and comparison with corticotropin therapy.
Neurology. 1972 Jun;22(6):603-10. doi: 10.1212/wnl.22.6.603.
5
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Neurology. 1971 Oct;21(10):1008-18. doi: 10.1212/wnl.21.10.1008.
6
Short-term intensive corticotrophin treatment in myasthenia gravis.重症肌无力的短期强化促肾上腺皮质激素治疗
Proc R Soc Med. 1971 May;64(5):492. doi: 10.1177/003591577106400516.
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