Jaratlerdsiri Weerachai, Rodríguez-Zárate Clara J, Isberg Sally R, Damayanti Chandramaya Siska, Miles Lee G, Chansue Nantarika, Moran Chris, Melville Lorna, Gongora Jaime
Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, RMC Gunn Building, University of Sydney, Sydney, New South Wales 2006, Australia.
J Virol. 2009 Oct;83(19):10305-8. doi: 10.1128/JVI.00668-09. Epub 2009 Jul 15.
Knowledge of endogenous retroviruses (ERVs) in crocodilians (Crocodylia) is limited, and their distribution among extant species is unclear. Here we analyzed the phylogenetic relationships of these retroelements in 20 species of crocodilians by studying the pro-pol gene. The results showed that crocodilian ERVs (CERVs) cluster into two major clades (CERV 1 and CERV 2). CERV 1 clustered as a sister group of the genus Gammaretrovirus, while CERV 2 clustered distantly with respect to all known ERVs. Interestingly, CERV 1 was found only in crocodiles (Crocodylidae). The data generated here could assist future studies aimed at identifying orthologous and paralogous ERVs among crocodilians.
人们对鳄鱼（鳄目）体内内源性逆转录病毒（ERVs）的了解有限，且不清楚它们在现存物种中的分布情况。在此，我们通过研究前多聚蛋白基因，分析了20种鳄鱼中这些逆转元件的系统发育关系。结果表明，鳄鱼内源性逆转录病毒（CERVs）聚为两个主要分支（CERV 1和CERV 2）。CERV 1聚为γ逆转录病毒属的姐妹群，而CERV 2与所有已知的ERVs聚类较远。有趣的是，CERV 1仅在真鳄科中发现。此处生成的数据可为未来旨在鉴定鳄鱼中直系同源和旁系同源ERVs的研究提供帮助。
