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伴有纯红细胞再生障碍性贫血的古德综合征。

Good syndrome accompanied by pure red cell aplasia.

作者信息

Taniguchi Tetsuo, Usami Noriyasu, Kawaguchi Koji, Yokoi Kohei

机构信息

Division of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

出版信息

Interact Cardiovasc Thorac Surg. 2009 Oct;9(4):750-2. doi: 10.1510/icvts.2009.210393. Epub 2009 Jul 16.

Abstract

Thymomas are often associated with various autoimmune disorders. We herein report a middle-aged female patient with thymoma and hypogammaglobulinemia (Good syndrome) who developed symptomatic normocytic anemia. Her computed tomography (CT) scans showed a cervico-mediastinal mass. The findings of a bone marrow biopsy suggested pure red cell aplasia (PRCA), and the serum levels of all immunoglobulins were extremely low. After the resection of the tumor, which was diagnosed to be Masaoka stage II and type AB thymoma, the normocytic anemia dramatically improved, but the hypogammaglobulinemia did not recover.

摘要

胸腺瘤常与各种自身免疫性疾病相关。我们在此报告一名患有胸腺瘤和低丙种球蛋白血症(古德综合征)的中年女性患者,她出现了症状性正细胞性贫血。她的计算机断层扫描(CT)显示颈纵隔肿块。骨髓活检结果提示纯红细胞再生障碍(PRCA),所有免疫球蛋白的血清水平极低。在切除被诊断为马萨oka II期和AB型胸腺瘤的肿瘤后,正细胞性贫血显著改善,但低丙种球蛋白血症未恢复。

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