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加味逍遥散治疗功能性消化不良的疗效研究。

Study on the effect of Jia-Wei-Xiao-Yao-San decoction on patients with functional dyspepsia.

机构信息

Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, Shannxi, PR China.

出版信息

Phytother Res. 2010 Feb;24(2):245-8. doi: 10.1002/ptr.2920.

Abstract

The effect of Jia-Wei-Xiao-Yao-San (JWXYS) decoction on patients with functional dyspepsia was studied by means of electrogastrography (EGG) and symptoms of dyspepsia were assessed. Twenty patients with functional dyspepsia were selected; before and after internal treatment with JWXYS, the integrated symptoms of the patients were down-regulated from 18.55 +/- 3.24 (before treatment) to 11.65 +/- 2.37 (after treatment) (p < 0.01); electrogastrography showed that all the EGG parameters of the patients were outside the normal range. After treatment with JWXYS, all these indices improved before and after dinner. The results showed that the JWXYS decoction could not only improve the symptoms, but also adjust the abnormal gastric motility and gastric myoelectrical activity of patients with functional dyspepsia.

摘要

采用胃电图(EGG)观察加味逍遥散对功能性消化不良患者的影响,并对其消化不良症状进行评估。选择功能性消化不良患者 20 例,采用加味逍遥散进行内治疗,治疗前后患者综合症状积分由治疗前的 18.55±3.24 下调至治疗后的 11.65±2.37(p<0.01);胃电图显示患者所有 EGG 参数均超出正常范围,加味逍遥散治疗后,患者餐前、餐后各指标均有改善。结果表明,加味逍遥散不仅能改善症状,而且能调整功能性消化不良患者的异常胃动力和胃电活动。

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