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使用放射变色EBT胶片叠层在浅表建成区进行光子束剂量测定。

Photon beam dosimetry in the superficial buildup region using radiochromic EBT film stack.

作者信息

Chiu-Tsao Sou-Tung, Chan Maria F

机构信息

Quality MediPhys LLC, 17 Jade Lane, Denville, New Jersey 07834, USA.

出版信息

Med Phys. 2009 Jun;36(6):2074-83. doi: 10.1118/1.3125134.

Abstract

It has been a challenge to perform accurate 2D or 3D dosimetry in the surface region with steep dose gradient for megavoltage photon beams. We developed a dosimetry method in the superficial buildup region for the 6 and 15 MV photon beams using a radiochromic EBT film stack. Eight radiochromic EBT film strips (3 x 20 x 0.024 cm3) stacked together formed a 3D dosimeter. The film stack was positioned above a polystyrene phantom and surrounded by Solid Water slabs (0.2 cm) with the top film layer at 100 cm SSD. A 10 x 10 cm2 open field was used to irradiate the film stack with 1000 MU. All films were scanned using Epson 4870 flatbed scanner with transmission mode, 48 bit color, and 150 dpi (0.017 cm pixel resolution). The pixel values were converted to doses using an established calibration curve. This method allowed dose measurement for depths from 0.012 to 0.18 cm with fine spatial resolution (0.017 cm horizontally and 0.024 cm vertically). For each energy modality, we obtained both the central axis percent depth doses and the beam profiles along the central line covering the primary field and peripheral region at each depth. The primary field doses varied steeply with depth, while those in the peripheral region were weakly dependent on depth. For the 6 MV and 15 MV photon beams, (1) the central axis percent depth doses in the eight film layers ranged from 22% to 66% and from 15% to 44%, respectively; (2) the extrapolated percent depth doses at d = 0 were 15% and 14%, respectively. Agreement with the previously reported central axis percent depth doses in this region using parallel plate thin window ion chamber and ultrathin TLD was observed. The percent depth doses and beam profiles data can be incorporated in the treatment planning system for more accurate assessment of the doses to skin and shallow tumors to accomplish more accurate calculation results in the clinical usage.

摘要

对于兆伏级光子束,在具有陡峭剂量梯度的表面区域进行精确的二维或三维剂量测定一直是一项挑战。我们使用放射变色EBT薄膜叠层开发了一种针对6和15兆伏光子束的浅表建成区剂量测定方法。八个放射变色EBT薄膜条(3×20×0.024立方厘米)堆叠在一起形成一个三维剂量计。薄膜叠层放置在聚苯乙烯模体上方,并用固体水板(0.2厘米)包围,顶部薄膜层位于100厘米源皮距处。使用10×10平方厘米的开放射野以1000MU照射薄膜叠层。所有薄膜均使用爱普生4870平板扫描仪在透射模式、48位颜色和150dpi(0.017厘米像素分辨率)下进行扫描。像素值使用既定的校准曲线转换为剂量。该方法允许在0.012至0.18厘米的深度进行剂量测量,具有精细的空间分辨率(水平0.017厘米,垂直0.024厘米)。对于每种能量模式,我们获得了中心轴百分深度剂量以及沿中心线覆盖每个深度的主野和周边区域的射野剖面。主野剂量随深度急剧变化,而周边区域的剂量对深度的依赖性较弱。对于6兆伏和15兆伏光子束,(1)八个薄膜层中的中心轴百分深度剂量分别为22%至66%和15%至44%;(2)在d = 0处的外推百分深度剂量分别为15%和14%。观察到与先前使用平行板薄窗电离室和超薄热释光剂量计在该区域报道的中心轴百分深度剂量一致。百分深度剂量和射野剖面数据可纳入治疗计划系统,以更准确地评估皮肤和浅表肿瘤的剂量,从而在临床应用中获得更准确的计算结果。

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