MMWR Morb Mortal Wkly Rep. 1991 Dec 13;40(49):841-4.
Outbreaks of influenza A virus infection can cause substantial morbidity and mortality among residents of nursing homes. Surveillance for the 1991-92 influenza season indicates that the dominant circulating viruses are influenza A (1), for which amantadine hydrochloride is effective for prevention and treatment (2). This report describes the use of amantadine as an adjunct to influenza vaccine for controlling an influenza A(H3N2) outbreak that occurred in a Washington nursing home during the 1989-90 influenza season.
甲型流感病毒感染的爆发可在疗养院居民中导致大量发病和死亡。1991 - 1992年流感季节的监测表明,主要流行的病毒是甲型(H1N1)流感病毒,盐酸金刚烷胺对其预防和治疗有效。本报告描述了在1989 - 1990年流感季节,华盛顿一家疗养院发生甲型(H3N2)流感爆发期间,使用金刚烷胺作为流感疫苗的辅助手段来控制疫情的情况。