Brzecka A, Rudkowska-Brzecka A
I Kliniki Chorób Płuc.
Neurol Neurochir Pol. 1991 May-Jun;25(3):301-6.
Polysomnographic studies were performed in 6 patients with obstructive sleep apnoea syndrome (OSA). The sleep study consisted of: electroencephalography, electromyography, electrooculography, electrocardiography, pulse oximetry and observation of respiration. During day multiple sleep latency tests were performed. In all patients fragmentation of sleep with prevalent stages 1. and 2. of NREM and occasionally deep sleep and REM phase were observed. Concomitantly with the appearance of electrophysiologic sleep stages the muscle tone decreased and episodes of obstructive apnoea occurred. The periods of sleep and apnoea alternated with wakefulness and breathing. In MSLF the mean latency was 3 +/- 2 min. In OSA syndrome episodes of obstructive sleep apnoea cause sleep fragmentation and prevalence of light sleep stages. Excessive daytime somnolence observed in this syndrome is caused by sleep disturbances. MSLT demonstrated pathologic hypersomnolence in OSA syndrome.
对6例阻塞性睡眠呼吸暂停综合征（OSA）患者进行了多导睡眠图研究。睡眠研究包括：脑电图、肌电图、眼电图、心电图、脉搏血氧饱和度测定和呼吸观察。白天进行了多次睡眠潜伏期测试。在所有患者中，均观察到睡眠碎片化，以非快速眼动睡眠（NREM）的1期和2期为主，偶尔出现深度睡眠和快速眼动睡眠期。随着电生理睡眠阶段的出现，肌张力下降，出现阻塞性呼吸暂停发作。睡眠期和呼吸暂停期与清醒期和呼吸交替出现。在多次睡眠潜伏期试验（MSLT）中，平均潜伏期为3±2分钟。在OSA综合征中，阻塞性睡眠呼吸暂停发作导致睡眠碎片化和浅睡眠阶段占优势。该综合征中观察到的白天过度嗜睡是由睡眠障碍引起的。多次睡眠潜伏期试验（MSLT）显示OSA综合征存在病理性嗜睡。
