Hodoba D, Perusić D, Zdravković V, Goldoni V, Dürrigl V
University Psychiatric Hospital Vrapce, Zagreb, Croatia.
Neurol Croat. 1991;40(4):293-305.
Eighteen (18) obese patients with clinically confirmed obstructive sleep apnea syndrome (OSAS) and five (5) obese persons with no apnea crises noticed during sleep apart from occassional loud snoring, have been polysomnographically assessed. The obtained results show that the patients with apnea syndrome sleep very badly, and consequently, shortened sleep latency and frequent body movements, along with apneas, are regarded as the leading polysomnographic symptoms. Vigilance profile during sleep, that is, interchange and frequency of each of sleep stages (I, II, III, IV, REM) are similar in both tested groups. The suppression of restitutive stages of sleep (III, IV, REM) is considered to be a dominant characteristic of vigilance during sleep in obese persons and obese persons with manifest apnea syndrome. Relatively prolonged sleep latency in obese persons without manifest apnea syndrome indicates, however, restitutively higher quality of their nocturnal sleep. Contrary to the patients with apnea syndrome, they do not suffer from excessive evening somnolence, so that their daily alertness and sleep vigilance during night are of a better quality, although the lack of deep and REM sleep is observed in them as well.
18例经临床确诊为阻塞性睡眠呼吸暂停综合征（OSAS）的肥胖患者和5例除偶尔大声打鼾外睡眠期间未出现呼吸暂停危机的肥胖者接受了多导睡眠图评估。所得结果显示，呼吸暂停综合征患者睡眠质量极差，因此，睡眠潜伏期缩短、频繁的身体活动以及呼吸暂停被视为主要的多导睡眠图症状。两组受试对象睡眠期间的警觉状态，即每个睡眠阶段（I、II、III、IV、快速眼动期）的交替和频率相似。睡眠恢复阶段（III、IV、快速眼动期）受到抑制被认为是肥胖者和患有明显呼吸暂停综合征的肥胖者睡眠期间警觉状态的主要特征。然而，无明显呼吸暂停综合征的肥胖者睡眠潜伏期相对延长表明其夜间睡眠质量在恢复方面更高。与呼吸暂停综合征患者相反，他们没有夜间过度嗜睡的情况，因此他们白天的警觉性和夜间的睡眠警觉性质量更好，尽管他们也存在缺乏深度睡眠和快速眼动睡眠的情况。
