苯乙醇胺N-甲基转移酶和多巴胺-β-羟化酶抑制对脑中肾上腺素水平的影响。 - Suppr

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Effect of phenylethanolamine N-methyltransferase and dopamine-beta-hydroxylase inhibition on epinephrine levels in the brain.

作者信息

Sauter A M, Lew J Y, Baba Y, Goldstein M

出版信息

Life Sci. 1977 Jul 15;21(2):261-6. doi: 10.1016/0024-3205(77)90310-1.

DOI:10.1016/0024-3205(77)90310-1

PMID:196153

Abstract

摘要

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Effect of phenylethanolamine N-methyltransferase and dopamine-beta-hydroxylase inhibition on epinephrine levels in the brain.苯乙醇胺N-甲基转移酶和多巴胺-β-羟化酶抑制对脑中肾上腺素水平的影响。

Life Sci. 1977 Jul 15;21(2):261-6. doi: 10.1016/0024-3205(77)90310-1.

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Gen Comp Endocrinol. 1995 Jan;97(1):121-34. doi: 10.1006/gcen.1995.1012.

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Effects of morphine administration on catecholamine levels in rat brain; specific reduction of epinephrine concentration in hypothalamus.吗啡给药对大鼠脑内儿茶酚胺水平的影响；下丘脑肾上腺素浓度的特异性降低。

Neurosci Lett. 1991 Jan 2;121(1-2):129-32. doi: 10.1016/0304-3940(91)90666-h.

Inhibitors of phenylethanolamine-N-methyltransferase. 2. Comparison of nonaromatic analogs of phenylethanolamines, 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline (SKF-64139) and 2,3-dichloro-alpha-methylbenzylamine: effects on rat brain and adrenal catecholamine content and blood pressure.苯乙醇胺 - N - 甲基转移酶抑制剂。2. 苯乙醇胺的非芳香类似物、7,8 - 二氯 - 1,2,3,4 - 四氢异喹啉（SKF - 64139）和2,3 - 二氯 - α - 甲基苄胺的比较：对大鼠脑和肾上腺儿茶酚胺含量及血压的影响。

J Pharmacol Exp Ther. 1982 Nov;223(2):382-7.

Inhibition of brain epinephrine synthesis by 3,4-dichlorophenylethanolamine, a competitive substrate for norepinephrine N-methyltransferase.

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Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.脑肾上腺素能神经元功能作用的评估：苯乙醇胺N-甲基转移酶抑制剂和α肾上腺素能受体拮抗剂对脑去甲肾上腺素代谢的长期影响。

J Pharmacol Exp Ther. 1984 Sep;230(3):577-86.

引用本文的文献

Further evidence for a correlation between EEG synchronization and plasma DBH activity in normal subjects.正常受试者脑电图同步性与血浆多巴胺β-羟化酶活性之间相关性的进一步证据。

J Neural Transm. 1980;49(3):167-78. doi: 10.1007/BF01245222.

Regulation of episodic growth hormone secretion by the central epinephrine system. Studies in the chronically cannulated rat.中枢肾上腺素能系统对生长激素脉冲式分泌的调节。对长期插管大鼠的研究。

J Clin Invest. 1982 Jan;69(1):104-12. doi: 10.1172/jci110420.

Role of brainstem and spinal noradrenergic and adrenergic neurons in the development and maintenance of hypertension in spontaneously hypertensive rats.脑干及脊髓去甲肾上腺素能和肾上腺素能神经元在自发性高血压大鼠高血压发生及维持中的作用

Naunyn Schmiedebergs Arch Pharmacol. 1978 Nov;305(2):127-33. doi: 10.1007/BF00508282.

Distribution of PNMT and epinephrine in the medulla oblongata of normotensive and spontaneous hypertensive rats.正常血压大鼠和自发性高血压大鼠延髓中苯乙醇胺N-甲基转移酶和肾上腺素的分布

J Neural Transm. 1979;44(4):309-16. doi: 10.1007/BF01250326.

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