Drago Francesco, Broccolo Francesco, Rebora Alfredo
Department of Endocrinological and Metabolic Sciences, Section of Dermatology, University of Genoa, Genoa, Italy.
J Am Acad Dermatol. 2009 Aug;61(2):303-18. doi: 10.1016/j.jaad.2008.07.045.
Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and many epidemiologic data all suggest an infectious origin. A host of infectious agents have been incriminated, but, recently, human herpesvirus 6 and 7 have been extensively studied. The goal of this review is to outline the epidemiologic, clinical, histologic, and ultrastructural features of pityriasis rosea, but mainly to stress its possible human herpesvirus nature. In addition, clues have been added to help the reader to go through the complex subtleties of the virologic investigation.
玫瑰糠疹是一种急性自限性皮疹，其特征为躯干和四肢出现椭圆形红斑鳞屑性损害，通常不累及面部、头皮、手掌和足底。具有真正前驱症状性质的全身症状、类似于已知皮疹的临床特征以及许多流行病学数据均提示其具有感染源。许多感染因子都被认为与之有关，但最近，人类疱疹病毒6型和7型受到了广泛研究。本综述的目的是概述玫瑰糠疹的流行病学、临床、组织学和超微结构特征，但主要是强调其可能的人类疱疹病毒本质。此外，还添加了一些线索，以帮助读者梳理病毒学研究的复杂细微之处。
